Results 141 to 150 of about 3,057,903 (256)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Do Institutions Impact Innovation? [PDF]

open access: yes
This paper contributes to the literature on institutions and economic growth by conducting an empirical examination on the links between innovation and institutions.
Elmslie, Bruce, Tebaldi, Edinaldo
core  

Recomanacions de serveis bibliotecaris per a interns

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2006
International Federation of Library Association and Institutions
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Reforming Institutions: Where to Begin? [PDF]

open access: yes
Institutions promote growth—this view now holds firm ground. The task then is to ‘engineer’ growth promoting institutions. Endogeneity characterises institutions, for example, groups enjoying political power influence economic institutions but political ...
M. Idrees Khawaja, Sajawal Khan
core  

Comunitats multiculturals : directrius per al servei bibliotecari

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2007
International Federation of Library Association and Institutions
doaj  

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