Results 71 to 80 of about 5,881,292 (359)

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

An Unusual Case of Bilateral Vitreous Haemorrhage following Snake Bite

open access: yesCase Reports in Medicine, 2013
A-45-year-old man presented to us with diminution of vision in both eye following snake bite. On examination vision in the right eye (RE) was 6/36 and vision in left eye (LE) was hand movement positive and fundus examination revealed a subhyloid ...
Vipul Bhandari, Meenal Lohia
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Endogenous Political Institutions [PDF]

open access: yes
Political institutions influence economic policy, but they are themselves endogenous since they are chosen, in some way, by members of the polity. An important aspect of institutional design is how much society chooses to delegate unchecked power to its ...
Alberto Alesina   +2 more
core   +3 more sources

Visualising anthropomorphism as a creative communicative mode in Samit Basu and Ashish Padlekar’s The Tall Tales of Vishnu Sharma: Panchatantra

open access: yesCreativity Studies
In today’s ocular-centric era, vision and visuality play a significant role in representing ideas. This article analyses anthropomorphism as a communicative mode that helps readers comprehend a story’s underlying meaning, using a socio-semiotics ...
Cynthiya Rose J S, Bhuvaneswari R
doaj   +1 more source

Molecular Epidemiology of Human Papillomavirus

open access: yesJournal of the Formosan Medical Association, 2008
Human papillomavirus (HPV) has been considered to be an etiologic factor for anogenital cancers, such as cervical cancer and possibly a subset of cancers of the aerodigestive tract. These small, non-enveloped, double-stranded DNA viruses primarily infect
Talia Hoory   +3 more
doaj   +1 more source

Group-based financial institutions for the rural poor in Bangladesh: an institutional- and household-level analysis [PDF]

open access: yes
Table of Contents: Tables, Figures, Foreword, Acknowledgments, and Summary; 1. Introduction; 2. Determinants of the Placement and Outreach of Group-Based Financial Institutions:A County-Level Analysis; 3.
Ahmed, Akhter U.   +3 more
core   +1 more source

Higher education institutions : subject profile [PDF]

open access: yes, 2011
"This briefing provides an overview of Higher Education Institutions in Scotland.
Berry, Kate
core  

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Charter and Institution [PDF]

open access: yesRivista di estetica, 2014
This paper addresses the nature of the Charter as the basic document of the Institution, that is, the most important document that lends the institution its force. The “and” between Charter and Institution or the conjoining of Charter with Institution has two tasks to perform.
openaire   +4 more sources

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