Results 171 to 180 of about 6,791 (285)
3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee+10 more
wiley +1 more source
Efeitos simbólicos capitalizados pelos enfermeiros do Instituto Nacional de Câncer no Brasil (1980 – 1990) [PDF]
Maria Cristina Frères de Souza+4 more
openalex +1 more source
A novel microphysiological system that can mimic sterile or non‐sterile injury demonstrates that macrophage‐derived extracellular vesicles modulate neutrophil migratory responses to these different wound states. The model showed that resolution of inflammation through neutrophil reverse migration is driven by IL‐8 derived from extracellular vesicles ...
Kehinde Adebayo Babatunde+5 more
wiley +1 more source
Validation of a Lateral Flow Assay for Rapid Diagnosis of Histoplasmosis in Advanced HIV Disease, Buenos Aires, Argentina. [PDF]
Andreani M+6 more
europepmc +1 more source
Análise da sobrevida de pacientes com carcinoma hepatocelular atendidos no Instituto do Câncer do Estado de São Paulo [PDF]
Luciana Kikuchi
openalex +1 more source
GLed, a reversible lanthanide‐based GSH sensor that enables real‐time, single‐cell measurement of Gamma–Glutamyl Cysteine Ligase (GCL) activity ‐whose role in human T cells remains unclear‐ is developed. GLed directly links GCL activity to T cell effector functions and reveals its modulation by immunosuppressive drugs, identifying GCL as a critical ...
Francisco Fueyo‐González+9 more
wiley +1 more source
Avaliação da implementação da pesquisa de anticorpos irregulares com hemácias tratadas com enzima nos exames pré-transfusionais de pacientes com neoplasia maligna de mama do Instituto Nacional do Câncer [PDF]
Renato Nascimento da Costa
openalex +1 more source
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen+11 more
wiley +1 more source