Results 171 to 180 of about 7,665 (266)

IFN-α/β Signaling Is Required for CDG-Mediated CTL Generation and B Lymphocyte Activation. [PDF]

open access: yesPharmaceutics, 2022
Hamouda AEI   +4 more
europepmc   +1 more source

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

open access: yesAdvanced Science, EarlyView.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy   +16 more
wiley   +1 more source

New Quinoline Kinase Inhibitors With Good Selectivity for NAK Kinases and Anti-Tumor Activity Against Ewing Sarcoma. [PDF]

open access: yesArch Pharm (Weinheim)
Gentz CB   +17 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

open access: yesAdvanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård   +19 more
wiley   +1 more source

Streamlining <i>Bacillus</i> Strain Selection Against <i>Listeria monocytogenes</i> Using a Fluorescence-Based Infection Assay Integrated into a Multi-Tiered Validation Pipeline. [PDF]

open access: yesAntibiotics (Basel)
Lorente-Torres B   +20 more
europepmc   +1 more source

Systematic literature review of primary and secondary cervical cancer prevention programs in South America. [PDF]

open access: yesRev Panam Salud Publica, 2023
Gomes MLS   +7 more
europepmc   +1 more source

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

open access: yesAdvanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke   +14 more
wiley   +1 more source

Evaluation of the Analytical Performance of a Lateral Flow Assay for the Detection of Anti-Coccidioides Antibodies in Human Sera-Argentina. [PDF]

open access: yesJ Fungi (Basel)
Viale MN   +7 more
europepmc   +1 more source

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