Results 231 to 240 of about 517,391 (323)

Nutritional information needs and search behaviors in argentine oncology patients [PDF]

open access: yesRev Fac Cien Med Univ Nac Cordoba
Manzur KM, Kohan Cortada A.
europepmc   +1 more source

Desconexão no sistema de inovação no setor saúde: uma avaliação preliminar do caso brasileiro a partir de estatísticas de patentes e artigos [PDF]

open access: yes
This paper conjectures about a disconnection between the scientific and the technological dimensions of the Brazilian health innovation system. Statistics of patents and scientific papers are used in the investigation of this conjecture.
Catari Vilela Chaves   +1 more
core  

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

open access: yesAdvanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli   +16 more
wiley   +1 more source

Autophagy-NAD<sup>+</sup> axis: emerging insights into neuronal homeostasis and neurodegenerative diseases. [PDF]

open access: yesFront Mol Biosci
Kocak G   +12 more
europepmc   +1 more source

Intestinal Neutral Ceramidase Deficiency Triggers Regulatory T Cell Response via Gd3 to Protect the Host from Intestinal Inflammation

open access: yesAdvanced Science, EarlyView.
Deletion of ASAH2 in intestinal epithelial cells induces the accumulation of ganglioside GD3 via regulating ST8SIA1. GD3 is identified as the glycolipid ligand for the inhibitory receptor Siglec‐E on macrophages. GD3/Siglec‐E ligation polarizes macrophages and promotes the proliferation of colonic ST2+ T regulatory cells via the induction of IL‐33. The
Zhishan Xu   +11 more
wiley   +1 more source

Microbiota-immune dysregulation in cervical cancer patients from Western Mexico: linking gut dysbiosis and NK cell exhaustion as promising biomarkers. [PDF]

open access: yesFront Immunol
Klimov-Kravtchenko K   +10 more
europepmc   +1 more source

Activation of USP30 Disrupts Endothelial Cell Function and Aggravates Acute Lung Injury Through Regulating the S‐Adenosylmethionine Cycle

open access: yesAdvanced Science, EarlyView.
USP30 deubiquitinates and stabilizes MAT2A, thereby regulating DNA methylation and miRNA expression, which ultimately leads to disruption of lung endothelial barrier and inflammation. Abstract Microvascular dysfunction is a key contributor to the development of acute inflammatory diseases, characterized by heightened vascular hyperpermeability and ...
Baoyinna Baoyinna   +11 more
wiley   +1 more source

TREATMENT OF GASTRIC CANCER ACCORDING TO THE COMPLEXITY OF THE HOSPITAL ONCOLOGY UNIT: ANALYSIS OF 33,774 PATIENTS OVER TWO DECADES. [PDF]

open access: yesArq Bras Cir Dig
Ramos MFKP   +7 more
europepmc   +1 more source

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