Results 91 to 100 of about 2,457,499 (300)
, 2018 To ensure that a robot is able to accomplish an extensive range of tasks, it is necessary to achieve a flexible combination of multiple behaviors. This is because the design of task motions suited to each situation would become increasingly difficult as ...
Mori, Hiroki +2 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Spiritual writings and religious instruction [PDF]
, 2008 As soon as a would-be writer picked up the pen in this period, he (or just occasionally she) had to make a far-reaching decision: whether to write in English, Anglo-Norman or Latin. The answer would emerge from the intersection of the text's genre and of
Barratt, Alexandra
core +1 more source
On the complexity of the correctness problem for non-zeroness test instruction sequences
, 2019 This paper concerns the question to what extent it can be efficiently determined whether an arbitrary program correctly solves a given problem. This question is investigated with programs of a very simple form, namely instruction sequences, and a very ...
Bergstra, J. A., Middelburg, C. A.
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
A progression ring for interfaces of instruction sequences, threads, and services [PDF]
, 2009 We define focus-method interfaces and some connections between such interfaces and instruction sequences, giving rise to instruction sequence components. We provide a flexible and practical notation for interfaces using an abstract datatype specification
Bergstra, Jan A., Ponse, Alban
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The discourses of doing science in English [PDF]
, 2006 In January 2003, Malaysia re-adopted the English language as a medium of instruction for science and mathematics. This change in the medium of instruction brings with it challenges of its own.
Jamilah Mustafa, +2 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source