Results 91 to 100 of about 903,001 (251)
, 1968 "Standards for accrediting Kansas secondary schools may be found in Bulletins 101 and 201. The purpose of Bulletin 201-A is to recommend certain guidelines that are, in most instances, over and above the minimum accreditation requirements as set forth by
Vigneron, John H., 1924-2003.
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, 2023 Nursing education in the 21st century faces several challenges, including a changing healthcare environment and rapid advances in medical knowledge and technology.
Buran-Omar, Anabelle P. +2 more
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Primary School Teachers’ Knowledge, Attitude and Practice of Differentiated Instruction [PDF]
, 2020 this study explored primary school teachers’ knowledge, attitude and practice of differentiated instruction. The target population of this study was primary school (Grades 1-4) teachers of the Amhara Region who were attending summer in-service diploma ...
Mengistie, Solomon Melesse
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Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Rules, regulations, standards, and procedures for accrediting high schools.
, 1968 Revised 1968"High schools interested in higher qualitative standards should use the following publications prepared by the State Department of Public Instruction: 'Guidelines for Improving Kansas Secondary Schools,' 'Evaluation Guide for Kansas High ...
Kansas. State Department of Public Instruction.
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source