Results 91 to 100 of about 1,478,008 (318)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

An efficient implementation of Slater-Condon rules [PDF]

open access: yes, 2013
Slater-Condon rules are at the heart of any quantum chemistry method as they allow to simplify $3N$-dimensional integrals as sums of 3- or 6-dimensional integrals.
Giner, Emmanuel, Scemama, Anthony
core  

DiVM: Model Checking with LLVM and Graph Memory

open access: yes, 2017
In this paper, we introduce the concept of a virtual machine with graph-organised memory as a versatile backend for both explicit-state and abstraction-driven verification of software. Our virtual machine uses the LLVM IR as its instruction set, enriched
Barnat, Jiří   +3 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

RISQ-reduced instruction set quantum computers [PDF]

open access: green, 2000
Klaus M⊘lmer   +1 more
openalex   +2 more sources

Rutger's CAM2000 chip architecture [PDF]

open access: yes
This report describes the architecture and instruction set of the Rutgers CAM2000 memory chip. The CAM2000 combines features of Associative Processing (AP), Content Addressable Memory (CAM), and Dynamic Random Access Memory (DRAM) in a single chip ...
Hall, J. Storrs   +2 more
core   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

A malware instruction set for behavior-based analysis [PDF]

open access: yes, 2009
We introduce a new representation for monitored behavior of malicious software called Malware Instruction Set (MIST). The representation is optimized for effective and efficient analysis of behavior using data mining and machine learning techniques.
Holz, Thorsten   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy