Results 91 to 100 of about 8,185,322 (352)

Quantum compiling with a variational instruction set for accurate and fast quantum computing

Physical Review Research, 2023
The quantum instruction set (QIS) is defined as the quantum gates that are physically realizable by controlling the qubits in quantum hardware. Compiling quantum circuits into the product of the gates in a properly defined QIS is a fundamental step in ...
Ying Lu, Peng-Fei Zhou, Shao-Ming Fei, Shi-Ju Ran   +3 more
doaj   +1 more source

Virtual Platforms for Instruction Set Simulation [PDF]

, 2014
Tato práce se zabývá vytvořením generátorů kódu pro existující virtuální platformy QEMU a OVP. Práce se skládá ze studie technik, které používají ke své práci virtuální stroje.
Ministr, Martin
core  

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Invalidating Analysis Knowledge for Code Virtualization Protection Through Partition Diversity

IEEE Access, 2019
To protect programs from unauthorized analysis, virtualize the code based on Virtual Machine (VM) technologies is emerging as a feasible method for accomplishing code obfuscation.
Wei Wang, Meng Li, Zhanyong Tang, Huanting Wang, Guixin Ye, Fuwei Wang, Jie Ren, Xiaoqing Gong, Dingyi Fang, Zheng Wang   +9 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Holistic debugging - enabling instruction set simulation for software quality assurance [PDF]

, 2006
We present holistic debugging, a novel method for observing execution of complex and distributed software. It builds on an instruction set simulator, which provides reproducible experiments and non-intrusive probing of state in a distributed system ...
Albertsson, Lars
core   +2 more sources

Impact of an introductory lab on students' understanding of measurement uncertainty

, 2017
Physics lab courses are an essential part of the physics undergraduate curriculum. Learning goals for these classes often include the ability to interpret measurements and uncertainties.
Dounas-Frazer, Dimitri R., Hobbs, Robert, Lewandowski, H. J., Pollard, Benjamin, Stanley, Jacob T.   +4 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Gated-Attention Architectures for Task-Oriented Language Grounding

, 2018
To perform tasks specified by natural language instructions, autonomous agents need to extract semantically meaningful representations of language and map it to visual elements and actions in the environment. This problem is called task-oriented language
Chaplot, Devendra Singh, Pasumarthi, Rama Kumar, Rajagopal, Dheeraj, Salakhutdinov, Ruslan, Sathyendra, Kanthashree Mysore   +4 more
core   +1 more source