Results 121 to 130 of about 8,185,322 (352)
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
The case against stack-oriented instruction sets [PDF]
, 1977 Glenford J. Myers
openalex +1 more source
Modeling of a latent fault detector in a digital system [PDF]
Methods of modeling the detection time or latency period of a hardware fault in a digital system are proposed that explain how a computer detects faults in a computational mode.
Nagel, P. M.
core +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
A language-oriented instruction set for the BALM language [PDF]
, 1973 Malcolm C. Harrison
openalex +1 more source
Standards for Proficiencies for Instruction Librarians and Coordinators [PDF]
, 2007 As the role of instruction and information literacy continues to grow in the academic library, librarians are faced with a need to develop a more focused set of skills to teach effectively in library instruction programs. At the same time, many libraries
Buss, Carla Wilson +3 more
core
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
The helping hand: How to bias kinesthetic aftereffects by instructional set [PDF]
, 1973 Daniel J. Weintraubt, Anita Caplan
openalex +1 more source
The distribution of amorphous computer outputs [PDF]
, 2005 Fitness distributions (landscapes) of programs tend to a limit as they get bigger. Markov minorization gives upper bounds ((15.3 + 2.30m)/ log I) on the length of program run on random or average computing devices.
Langdon, W.B.
core
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source