Results 181 to 190 of about 86,965,910 (255)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

RETRACTED: Dopelt et al. (2025). What Drives the Non-Medical Use of Stimulants Among College Students? The Role of Self-Efficacy and Attitudes: A Cross-Sectional Study of Israeli Undergraduates. <i>European Journal of Investigation in Health, Psychology and Education</i>, <i>15</i>(7), 141. [PDF]

Eur J Investig Health Psychol Educ
Dopelt K, Bord S, Houminer-Klepar N.
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Mayo Test Drive Español: A model of digital cognitive test adaptation. [PDF]

Clin Neuropsychol
Karstens AJ, Aduen PA, Luna Andrade N, Diaz-Galvan P, Barber M, Woolston DJ, Patel JS, Stricker JL, Hassenstab J, Lucas JA, Lachner C, Stricker NH.   +11 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Dispatcher-assisted AED use in single-rescuer cardiac arrest: study protocol for a randomized simulation study comparing standard and optimized dispatcher-assisted CPR instructions. [PDF]

Resusc Plus
Balassa B, Bánfai-Csonka H, Betlehem J, Böttiger BW, Bánfai B.   +4 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Editorial (2026, issue 5, September/October). [PDF]

Photochem Photobiol
Greer A.
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Determinants of digital home spirometer use and quality parameters in management of patients with chronic obstructive respiratory disease and asthma in general practice: a mixed methods study. [PDF]

BMC Health Serv Res
Cummerow J, Strobel CJ, Goetz K, Steinhäuser J.   +3 more
europepmc   +1 more source