Results 61 to 70 of about 86,965,910 (255)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

The History and Implications of the Medical Education Accreditation System in Korea: Implementation and Activities in Early Stages [PDF]

open access: yes, 2020
Following the opening of eleven medical schools in Korea in the 1980s, the issues of standardization and accreditation of medical education came to the forefront in the early 1990s.
Korean Medical Education Review (의학교육논단)
core   +1 more source

Standard instructions for medical use of interchangeable drugs: analysis of modern regulatory documents

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
The article presents a review of modern regulatory and legal framework and draft regulatory documents on circulation of interchangeable drugs with regard to standard instructions for medical use. The analysis included more than 70 documents.
M. V. Zhuravleva   +8 more
doaj  

The need to transition from paper to electronic instructions for use for diabetes devices

open access: yesnpj Digital Medicine
Regulatory agencies, such as the European Commission and the U.S. Food and Drug Administration, are now permitting electronic instructions for use (eIFUs) to be distributed alongside paper instructions for use (IFUs) for medical devices.
Cindy N. Ho   +3 more
doaj   +1 more source

Designing for Knowledge Generalization in Medical Device Instructions Among Health Care Professionals: Qualitative Interview and Observation Study

open access: yesJMIR Human Factors
BackgroundInstructional documents are crucial for safely operating medical devices. However, few studies have explicitly considered designing instructions for health care professionals (HCPs).
Qing (Nancy) Xia   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Medical eligibility criteria for contraceptive use [PDF]

open access: yes
"CDC created U.S. Medical Eligibility Criteria for Contraceptive Use, 2010, from guidance developed by the World Health Organization (WHO) and finalized the recommendations after consultation with a group of health professionals who met in Atlanta ...
National Center for Chronic Disease Prevention and Health Promotion (U.S.) Division of Reproductive Health.
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Designing instructions for use for in vitro diagnostic medical devices [PDF]

open access: yes, 2017
33 p.This technical guidance document provides recommendations for manufacturers developing instructions for use (IFU) for in vitro diagnostic medical devices (IVDs) intended for WHO prequalification.
World Health Organization
core  

Ethnomedicinal Uses, Phytochemistry and Pharmacology of Dorema Species (Apiaceae): A Review

open access: yesJournal of Pharmacopuncture, 2020
The application of antique medical instructions, practices, skills and knowledge has been considered as the most affordable treatment in many developing countries.
Elaheh Zibaee   +6 more
doaj   +1 more source

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