Results 91 to 100 of about 179,013,531 (163)

Levellism and the Method of Abstraction by

, 2008
The use of “levels of abstraction ” in philosophical analysis (levellism) has recently come under attack. In this paper, we argue that a refined version of epistemological levellism should be retained as a fundamental method, which we call the method of ...
The Method Of Abstraction, Luciano Floridi   +1 more
core  

Ptbp1 Condensates With Phase Separation‐Like Features in Cardiomyocyte Nuclei Regulate Splicing of Proliferative Genes in Neonatal Cardiomyocytes

Development, Growth &Differentiation, Volume 68, Issue 8, October 2026.
Phase‐separated Ptbp1 droplets form molecular complexes containing multiple proliferation‐associated molecules. Ptbp1 granules containing four RNA recognition motifs (RRMs) domains are present in the nuclei of mouse cardiomyocytes specifically during the proliferative stage.
Tai Sada, Akane Sakaguchi, Yoichi Shinkai, Reiko Nakagawa, Chiharu Tanegashima, Mitsutaka Kadota, Takefumi Kondo, Wataru Kimura   +7 more
wiley   +1 more source

Neural Cell Models of Specific Reading Disabilities: Identification of Cellular and Transcriptome Alterations

Genes, Brain and Behavior, Volume 25, Issue 5, October 2026.
Neural cell phenotypes were tested using cells derived from two pairs of siblings strongly discordant for reading—probands with severe RD and their strong‐reader siblings. We observed significant differences in outgrowth in the neurosphere assay using the neural precursor cells (NPCs) derived from the probands compared to cells from their strong‐reader
Cathy L. Barr, Karen G. Wigg, Yu Feng, Kirsten Blokland, Margaret Wilkinson, Elizabeth N. Kerr, Sharon L. Guger, Maureen W. Lovett, Lisa J. Strug, Ruth Oefner, Simone Benassi, Fred H. Gage, Maria C. Marchetto   +12 more
wiley   +1 more source

Learning‐based cognitive control in ADHD: a multicentric study

Journal of Child Psychology and Psychiatry, Volume 67, Issue 10, Page 1624-1638, October 2026.
Background Learning‐based cognitive control (CC), the ability to adapt control strategies based on contextual regularities, has been studied in typically developing (TD) children but remains underexplored in children with attention deficit hyperactivity disorder (ADHD).
Lisa Toffoli, Giulia Stefanelli, Fiorella Del Popolo Cristaldi, Gian Marco Duma, Massimiliano Pastore, Vincenza Tarantino, Malida Franzoi, Marilena Vecchi, Alberto Danieli, Federica Martinez, Agnes Blaye, Corentin Gonthier, CALM‐1 Team, Giovanni Mento   +13 more
wiley   +1 more source

Role of the tomato MARS1/ROUGH gene encoding a LYSINE‐SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

Journal of Integrative Plant Biology, Volume 68, Issue 10, Page 3644-3669, October 2026.
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba, Cécile Bres, Aurora Alaguero‐Cordovilla, Riyazuddin Riyazuddin, Qingyi Wang, Johann Petit, Jean‐Philippe Mauxion, Lara Caballero, David Latrasse, Bénédicte Bakan, Rim Brik‐Chaouche, David Esteve‐Bruna, Moussa Benhamed, Christophe Rothan, José Manuel Pérez‐Pérez   +14 more
wiley   +1 more source

Estrogen/Esr2b signaling‐dependent, female‐biased expression of a neuropeptide Y gene in the medaka brain

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract A recent study showed that female medaka lacking the estrogen receptor gene esr2b are unreceptive to male courtship and instead court other females. In this study, we investigated the brain transcriptome of esr2b‐deficient females to explore the underlying mechanisms of this behavioral phenotype, and identified npyb, one of the two ...
Yuki Homan, Yuji Nishiike, Mika Sato‐Tsukamoto, Daisuke Saito, Mikita Suyama, Yasuyuki Ohkawa, Fumiya Takahashi, Takashi Baba, Ken‐ichirou Morohashi, Kataaki Okubo   +9 more
wiley   +1 more source

The combination of morphogenic regulators BABY BOOM and GRF‐GIF improves maize transformation efficiency and promotes leaf regeneration

New Phytologist, Volume 252, Issue 1, Page 260-275, October 2026.
Maize regeneration via somatic embryogenesis by ectopic expression of morphogenic factors TaGRF4‐TaGIF1 and ZmBBM. Summary Transformation is an indispensable tool for plant genetics and functional genomics. Although stable transformation in maize is no longer a major obstacle, there remains a need for accessible and efficient methods for academic ...
Zongliang Chen, Jiaqi Zhou, Mary Galli, Sessen Daniel Iohannes, Theresa Clark, Juan M. Debernardi, Jorge Dubcovsky, David Jackson, Andrea Gallavotti   +8 more
wiley   +1 more source

Global Recommendations for the Use of Diagnostic Genomic Sequencing in the Prenatal Setting on Behalf of the ESHG and ISPD

Prenatal Diagnosis, Volume 46, Issue 11, Page 1683-1702, October 2026.
Zandra C. Deans, Lina Basel Salmon, Kwong Wai Choy, Guido de Wert, Zirui Dong, Lilian Downie, Francesca Romana Grati, Sabine Hentze, Paula Jorge, Brynn Levy, Luca Lovrecic, Dora Mayen, Álvaro Mendes, Michael Morris, Ashley Pritchard, Raquel Gouveia Silva, Tina‐Marié Wessels, Francesca Forzano, Natalie J. Chandler   +18 more
wiley   +1 more source

Chinese Guideline on Risk Management of Osteoporosis in the General Public

Orthopaedic Surgery, Volume 18, Issue 10, Page 2015-2031, October 2026.
Summary of the background, key recommendations, and expected impact of the public guideline for osteoporosis risk management. ABSTRACT Background Osteoporosis is a common chronic skeletal disorder characterized by decreased bone mass and microarchitectural deterioration, resulting in increased fragility and fracture risk. With rapid population aging in
Shiyong Zhang, Jinqiu Yuan, Zhuojing Luo, Jiacan Su, Weibo Xia, Kehu Yang, Fuxin Wei, Osteoporosis Group, Chinese Association of Orthopaedic Surgeons, Youth Osteoporosis Group, Chinese Orthopaedic Association, Chinese Medical Association, Health Communication Branch, Chinese Preventive Medicine Association, Spine and Joint Health Branch, Guangdong Health Care Association, Chinese Health Risk Management Collaboration–Osteoporosis Group (CHRIMAC‐OP), Zhuojing Luo, Jiacan Su, Weibo Xia, Kehu Yang, Fuxin Wei, Jinqiu Yuan, Xiao Chen, Bo Gao, Yang Guo, Xiaofeng Gong, Junjie Huang, Yafang Huang, Tianyong Hou, Da He, Bin Liu, Yajun Liu, Fangping Li, Ying Li, Wei Li, Jiang Li, Zhihao Li, Xiahong Lin, Houqing Long, Jianwen Mo, Wenfei Ni, Yuanjun Teng, Liang Wang, Xiaobin Wang, Hongli Wang, Nan Wu, Hongfei Xiang, Bin Yan, Dejin Yang, Min Yang, Wei Ye, Hongping Yu, Ziji Zhang, Shiyong Zhang, Xinyu Chen, Ningning Chen, Qiangsheng He, Linmin Hu, Wenjing Li, Zijun Li, Qiji Li, Chengkai Lin, Qingfeng Luo, Tianyi Liu, Ningning Mi, Mina Ma, Jun Shen, Peng She, Huidong Tian, Siqing Wu, Junming Wan, Yongsheng Wang, Bin Xia, Peng Xie, Jinyu Zhao, Fei Zhang, Penghui Zhang, Danni Wang, Lei Cheng, Zhongshi Li, Xinyu Liu, Jing Wang, Shengping Yang, Binsheng Yu   +84 more
wiley   +1 more source

CPM-XNet: Annotation-Efficient Deep-Learning Framework for Detecting Tuberculosis in Chest X-Ray Images. [PDF]

Diagnostics (Basel)
Yang TC, Wang BY, Li JY, Chang YK, Lin SH, Chang CC, Chu YW.   +6 more
europepmc   +1 more source