Results 51 to 60 of about 11,087 (125)

A Non‐Canonical Core Transcriptional Regulatory Circuit Orchestrates Chromatin Reprogramming to Drive Osimertinib Resistance in Non‐Small Cell Lung Cancer

Advanced Science, Volume 13, Issue 46, 17 August 2026.
A non‐canonical core transcriptional regulatory circuit, composed of ID3, SMAD3, and NR2F2, drives Osimertinib resistance in non‐small cell lung cancer through super‐enhancer‐mediated activation of EPAS1, which couples neuroendocrine differentiation with ferroptosis evasion.
Aochu Liu, Zhenguo Liu, Lizhen Jiang, Andong Huang, Xinqing Lin, Xinyue Li, Bingyuan Liu, Shiwen Hu, Qiang Pan, Junjun Huang, Liyuan Yin, Liling Jiang, Wei Yi, Wenjun Mao, Yueyuan Zheng, Xianping Shi   +15 more
wiley   +1 more source

Differences in Immediate and Delayed Suggestibility Among Children With Dyslexia and Controls

Behavioral Sciences &the Law, Volume 44, Issue 4, Page 559-570, July/August 2026.
ABSTRACT The primary aim of this study was to investigate the relationship between dyslexia and suggestibility in children, and the extent to which this relationship is accounted for by performance on Word Tasks. Participants comprised 95 children with dyslexia and 109 controls.
Gisli Gudjonsson, Valeria Giostra, Monia Vagni   +2 more
wiley   +1 more source

Activation of a TFAM‐Dependent Mitochondrial Translational Axis Drives Oxidative Metabolism in Grade 2 Meningiomas

Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT Meningiomas exhibit marked biological heterogeneity that is not fully captured by current histopathological grading. Increasing evidence suggests that mitochondrial metabolism contributes to tumor aggressiveness; however, the molecular mechanisms regulating mitochondrial function in meningiomas remain poorly defined.
Stella G. Cavalcante, Benedito Jamilson Araújo Pereira, Antonio M. Lerario, Paula R. Sola, Sueli M. Oba‐Shinjo, Suely K. N. Marie   +5 more
wiley   +1 more source

Social Relationships and Experimental Pain Sensitivity in Healthy Adolescent Girls: An Exploratory Preliminary Study

European Journal of Pain, Volume 30, Issue 7, August 2026.
ABSTRACT Introduction Greater understanding of relationships between social factors and pain responses can provide new modifiable targets for pain interventions in adolescents. This observational preliminary exploratory study aims to examine the associations between experimental pain sensitivity and social factors in healthy adolescents.
Elizabeth Mulat, Gourav Banerjee, Rachel Cundiff‐O'Sullivan, Joel Brown, Alana McMichael, Philip Miller, Katelynn E. Boerner, Abbie Jordan, Hadas Nahman‐Averbuch   +8 more
wiley   +1 more source

Outcomes in the Management of Pediatric Retrograde Cricopharyngeal Dysfunction

The Laryngoscope, Volume 136, Issue 8, Page 3620-3626, August 2026.
ABSTRACT Objective To review the presentation and treatment outcomes of pediatric patients with retrograde cricopharyngeal dysfunction (RCPD). Methods A retrospective chart review was performed on pediatric patients diagnosed with retrograde cricopharyngeal dysfunction (RCPD) and treated with cricopharyngeal botulinum toxin injection (CPBTI).
Aidan P. Wright, Vivian Jin, Nathaniel B. Hunter, Andrew G. Tritter   +3 more
wiley   +1 more source

Navigating across individual and deliberative values: A dual Q‐method approach to elicit diverse values in grassland restoration

People and Nature, Volume 8, Issue 8, Page 2541-2558, August 2026.
Abstract The current ‘UN Decade on Restoration’ calls for collaboration between scientists and practitioners to formulate guidelines for ecosystem restoration, within which transdisciplinary approaches are imperative to rethink the diverse values associated with nature, paving the way for sustainable ecosystem restoration.
Miguel A. Cebrián‐Piqueras, Konrad Gray, Lukas Kuhn, Jacqueline Loos, Ioana A. Pătru‐Dușe, Maraja Riechers, Vicky Temperton, Berta Martín‐López   +7 more
wiley   +1 more source

Nitrogen Status Rewires Transcriptional Regulation of Dhurrin, a Dual‐Purpose Defense Metabolite in Sorghum bicolor

Plant Direct, Volume 10, Issue 8, August 2026.
ABSTRACT Dhurrin, a cyanogenic glucoside, plays an important role in Sorghum bicolor physiology and defense. The concentration of dhurrin in sorghum is influenced by both nitrogen status and stage of plant organ development. While nitrogen resupply activates the expression of genes for dhurrin biosynthesis, the molecular mechanisms underlying this ...
Alicia A. Quinn, Brian A. McKinley, Cecilia K. Blomstedt, John E. Mullet, Roslyn M. Gleadow   +4 more
wiley   +1 more source

Exploring the Development of Wild Microbiomes in the Eastern Fence Lizard

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
We used 16S rRNA gene sequencing to profile the bacterial community from the guts of wild Eastern Fence Lizards. Microbiome profiles were collected at four distinct time points when lizards were actively foraging in the environment and across four age groups, aiming to characterise the natural variation in bacterial diversity.
Michael S. Grapin, Justin Wright, Jeremy Chen See, Samantha Anderson, Regina Lamendella, John Matter   +5 more
wiley   +1 more source

Renal Phosphate Reabsorption in Humans Depends on at Least Three Distinct Transporters Unlike in Mice

Acta Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Aim Kidney excretion of phosphate is the gatekeeper of systemic phosphate homeostasis as evident from inborn and acquired diseases. Renal phosphate transporters are a promising target for phosphate‐lowering drugs, but molecular details of human kidney phosphate handling are largely unknown.
Ashley L. Fernandes, Laurine Lang, Jürgen Klar, Anja Giese, Alexander Ehrmann, Rupert Busch, Hannah Auwerx, Christoph Daniel, Nati Hernando, Isabel Rubio‐Aliaga, Carsten A. Wagner   +10 more
wiley   +1 more source

Integrated Transcriptomic and Functional Analyses Reveal lncRNA‐miRNA‐mRNA Axis in AML Relapse After Allo‐HSCT

Cancer Science, Volume 117, Issue 8, Page 2289-2304, August 2026.
Transcriptomic profiling of CD34+ cells from AML patients relapsing after allo‐HSCT reveals lncRNA‐driven ceRNA networks, with the SNHG8‐miR‐625‐ZC3H13/15 axis identified as a key relapse‐promoting module through CRISPR screening and single‐cell perturbation.
Fei Zhao, Wenhao Wang, Hongye Gao, Ping Zhu, Weihua Zhai, Yi He, Aiming Pang, Sizhou Feng, Mingzhe Han, Lina Wu, Shukai Qiao, Lei Zhang, Erlie Jiang, Xiaolei Pei, Donglin Yang   +14 more
wiley   +1 more source