Results 51 to 60 of about 179,013,531 (163)

Ploidy‐Dependent Response to Anticancer Drugs of Human Embryonic Stem Cells

Cell Proliferation, EarlyView.
Using isogenic hESCs, differing only in their ploidy level, we show the effect of ploidy on the resistance to anticancer drugs. We demonstrate that polyploidy, by itself, confers sensitivity to chemotherapies, leading to higher apoptosis and delayed proliferation, while the loss of p53 reverses the phenotype, demonstrating higher resistance.
Guy Haim‐Abadi, Nissim Benvenisty
wiley   +1 more source

Physical Activity and Sedentary Behaviour in Children With Haemophilia

Haemophilia, EarlyView.
ABSTRACT Introduction Physical activity (PA) is vital in child development, while inactivity remains a leading contributor to global mortality. Therapeutic advances have enabled greater PA in boys with haemophilia (BwH), yet robust UK data on objectively measured PA and sedentary behaviour (SB) across severities are limited.
Melanie Bladen, Lucy Alderson, Eleanor Main, Mario Cortina‐Borja   +3 more
wiley   +1 more source

Is It Time to Raise the Threshold for Critically Low Fibrinogen? Insights From a Retrospective, Consecutive‐Case Cohort Study of Low Fibrinogen due to Various Causes

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Fibrinogen deficiency is an important coagulation abnormality, with diverse causes. Methods A consecutive‐case cohort study of adult and pediatric patients with low Clauss fibrinogen at four acute care hospitals was undertaken to explore findings, causes, and predictors of outcomes, including the optimal fibrinogen critical value ...
Natalie Mathews, Subia Tasneem, Mana Al Dawsari, Keona Pang, Yasmeen Abulkhair, Guillame Paré, Siraj Mithoowani, Catherine P. M. Hayward   +7 more
wiley   +1 more source

The association between 24‐hr movement patterns and self‐harm incidence in adolescence

Journal of Child Psychology and Psychiatry, EarlyView.
Background Self‐harm is a pressing public health issue, particularly among adolescents. Physical activity is associated with reduced self‐harm among youths, but evidence is limited. Most studies rely on self‐reported measures and are primarily focused on moderate‐to‐vigorous physical activity (MVPA), often overlooking the role of light‐intensity ...
Siyi Huang, Jiameng Cui, Qida He, Shahmir H. Ali, Qi Wang, G. Neil Thomas, Linyan Li   +6 more
wiley   +1 more source

Improving Time-Cost Balance in Critical Path Method (CPM) Using Dragonfly Algorithm (DA) [PDF]

, 2019
The CPM (critical path method) technique is to search out the longest path to try and do activities, so as to compress and cut back the time it takes for a project, which finally ends up inside the creation of an identical and intensive network of ...
Amirhossein Mohebifar, Ali Mohammad Mosadeghrad, Mohmmad Anvar Adibhesami, Ahmad Ekhlassi   +3 more
core  

Analisis Perbandingan Penjadwalan Proyek Dengan Metode Critical Path Method (CPM) dan Critical Chain Project Management (CCPM)

, 2023
Pada proyek pembangunan offshore platform dibutuhkan penjadwalan yang baik agar seluruh proses dalam proyek berjalan dengan lancar. Metode yang paling umum digunakan dalam merencanakan proyek adalah dengan Critical Path Method (CPM).
Luthfi, Muhamad
core  

The Mean and Variability of Morning Hour Activity Over 2–3 Days Predict 5‐Year Mortality and Frailty Risk in a National Sample of Older Adults

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Activity pattern features measured by continuous accelerometry are strongly associated with frailty, making accelerometry a promising, scalable screening tool for frailty. However, adherence to typical 5–7 day wear protocols decreases with age, reducing feasibility.
Megan Huisingh‐Scheetz, Sylvia Brown, Michelangelo Pagan, Cassidy Cabrera, Daniel Rubin, Nabiel Mir, Maria Lucia Madariaga, L. Philip Schumm, Kristen Wroblewski, Donald Hedeker   +9 more
wiley   +1 more source

Community Midwifery Postpartum Care: National Data From Community Practice

Journal of Midwifery &Women's Health, EarlyView.
Introduction The United States is a global anomaly in its lack of postpartum care. Community midwives’ scope of practice generally includes maternal and infant care until 6 weeks after birth, although research on community midwifery postpartum care in the United States has been limited.
Ariana Thompson‐Lastad, Marit L. Bovbjerg, Jessica M. Harrison, Tanya Khemet Taiwo, Elise Erickson, Melissa Cheyney   +5 more
wiley   +1 more source

Barriers to Medicaid Participation for Community Midwives in California

Journal of Midwifery &Women's Health, EarlyView.
Introduction The United States faces persistent perinatal health care inequities, and there is growing recognition that midwifery care, including community‐based care offered outside of hospital settings, could address these challenges. Medicaid finances half of the births in the United States, but state policies notably limit access to community ...
Jessica M. Harrison, Ariana Thompson‐Lastad, Chanda Williams, Sara Jhanjar, Mounika Parimi, Jennifer T. Dunn, Maria T. Chao, Jennifer James, Liz Donnelly, Holly Smith, Tanya Khemet Taiwo   +10 more
wiley   +1 more source

Scheduling of Empennage Structure Design Project of Indonesia’s Aircraft with Critical Path Method (CPM)

, 2018
Production of the aircraft becomes very important to facilitate many passengers of aircraft in Indonesia in the future. The design of a very complex aircraft requires proper project management.
Farizal, Wulandari Arin, Dachyar M.
core   +1 more source