Results 101 to 110 of about 3,500,243 (336)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

[Cross-cultural adaptation of the instrument Appraisal of Guidelines For Research & Evaluation II (AGREE II) for assessment of clinical guidelines].

open access: yes, 2014
This article describes the adaptation of the Appraisal of Guidelines for Research & Evaluation II (AGREE II) instrument into Portuguese. A cross-cultural adaptation followed internationally accepted standards with the stages of translation, synthesis ...
Gleide Simas Custódio Khan   +2 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Upscaling aboveground biomass estimation at low-land royal belum forest reserve using unmanned aerial vehicle image [PDF]

open access: yes, 2018
Thermal properties of certain building materials were studied with respect to environmental aspects. The building materials with significant insulation properties were laboratory tested using the special equipment based on Peltier module.
Ahmad, Mustaffa Anjang   +7 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Translation and cross-cultural validation of the instrument “Spiritual Assessment Scale” in Brazil

open access: yesO Mundo da Saúde, 2013
Spirituality is considered an integrant part of nursing care. This study aimed to perform a cross-cultural adaptation of the “Spiritual Assessment Scale” (SAS) to Brazil. A specific instrument for cross-cultural adaptation based on Lynn’s studies (Likert
Elizangela Oliveira Freitas   +4 more
doaj  

Cross-cultural adaptation of Rotter's General Locus of Control instrument

open access: yesTrends in Psychiatry and Psychotherapy
Objective To perform a cross-cultural adaptation of the General Locus of Control (GLoC) questionnaire, which measures where people place causation of events in their lives, i.e., if they interpret events as being the result of their own actions or ...
Gabriel de Almeida Calado   +4 more
doaj   +1 more source

Peripheral visual response time to colored stimuli imaged on the horizontal meridian [PDF]

open access: yes
Two male observers were administered a binocular visual response time task to small (45 min arc), flashed, photopic stimuli at four dominant wavelengths (632 nm red; 583 nm yellow; 526 nm green; 464 nm blue) imaged across the horizontal retinal meridian.
Dawson, L. M.   +3 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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