Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
An instrument to measure the solar spectrum from 170 to 3200 nm on board Spacelab [PDF]
This instrument, at the present time in development, will fly on board Spacelab I in May 1983. Other flights are foreseen during the following missions. The instrument is composed of three double monochromators covering the range 170 to 3200 nm.
Labs, D. +4 more
core +1 more source
Development of Instruments to Train Critical and Creative Thinking Skills in Physics Assessment for High School Students’ Learning [PDF]
, 2019 R Herpiana +2 more
openalex +1 more source
Development of Numeracy Test Instrument of Minimum Competency Assessment (MCA) in Algebra and Geometry Contents [PDF]
, 2023 Noeri Itsnaniyah +2 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Development of a Ground-Based Aerial-Tracking Instrument for Open-Path Spectroscopy to Monitor Atmospheric Constituents [PDF]
, 2019 A ground-based aerial-tracking instrument, known as the Ground Tracker, designed to provide spectral data to quantify greenhouse gases is under development.
Hodges, Haden
core +2 more sources
ECONOMIC DEVELOPMENT, AGRICULTURE AND ENVIRONMENT IN BRAZIL: INSTRUMENTS AND POSSIBILITIES OF RECONCILIATION [PDF]
, 2008 Augusto Mussi Alvim +5 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Global Health Action, 2018 Background: External supervision of primary health care facilities to monitor and improve services is common in low-income countries. Currently there are no tools to measure the quality of support in external supervision in these countries.
Michael Schriver +4 more
doaj +1 more source
Mentoring Programmes as a successful instrument for career development of people with disabilities and disadvantaged [PDF]
, 2007 [Excerpt] For many years the Mentoring, as a form of support for young people without work experience, is well-known practice. In the past ten years the Mentoring has proved itself as a wide-applied method of support in the career of people with ...
Leonardo da Vinci Pilot Projects
core +1 more source