Results 101 to 110 of about 8,598,676 (340)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Construction Method of the Topographical Features Model for Underwater Terrain Navigation

open access: yesPolish Maritime Research, 2015
Terrain database is the reference basic for autonomous underwater vehicle (AUV) to implement underwater terrain navigation (UTN) functions, and is the important part of building topographical features model for UTN.
Wang Lihui, Yu Le, Zhu Yanhua
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Schooling and labor market impacts of a natural policy experiment [PDF]

open access: yes
The authors use a nationally representative household survey to estimate returns to schooling in Venezuela from instrumental variables based on a supply-side intervention in the education market.
Patrinos, Harry Anthony   +1 more
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Your PEL questionnaire development - evaluation of the impact of health education programs in schools. [PDF]

open access: yes, 2019
Artigo apresentado em Coimbra no âmbito do Anuual Meeting 2019 da Escola Superior de Tecnologia da SaúdeThe Your PEL project emerged in response to requests from regional school groups and community care units that have identified the need to assess the ...
Amendoeira, José   +9 more
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Design and Implementation of a Micromechanical Silicon Resonant Accelerometer

open access: yesSensors, 2013
The micromechanical silicon resonant accelerometer has attracted considerable attention in the research and development of high-precision MEMS accelerometers because of its output of quasi-digital signals, high sensitivity, high resolution, wide dynamic ...
Libin Huang   +4 more
doaj   +1 more source

The Effectiveness in Measuring Character Development Outcomes in Singapore Schools Through the Character Development Award [PDF]

open access: yes, 2010
In 2006, Singapore’s Ministry of Education started recognising schools for their effort in using effective character development programmes in producing holistic students who are both competent in their academic studies and possess good moral character ...
TEO, WILSON
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy