Results 121 to 130 of about 8,598,676 (340)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

A Hybrid Approach Based on Improved AR Model and MAA for INS/DVL Integrated Navigation Systems

open access: yesIEEE Access, 2019
In navigation of autonomous underwater vehicles (AUVs), the estimation of position is an important issue, especially, when the sensors such as gyroscopes contain a lot of noise, and the velocity information of Doppler velocity log (DVL) is affected by ...
Di Wang   +4 more
doaj   +1 more source

DEVELOPING INSTRUMENT OF MULTIPLE INTELLIGENCES BASED ON COMPUTER, A MODEL OF TRACING INTEREST AND APTITUDE OF SENIOR HIGH SCHOOL STUDENTS [PDF]

open access: yes, 2007
This research was based on three main reasons; fiirst, the development of intelligence theory not just oriented in cognitive aspect, so that originating theory of multiple intelligences; second, there was phenomenon of so many senior high school students
Farida Agus Setiawati, M.Si.
core  

Development of an Assessment of Student Conception of the Nature of Science [PDF]

open access: yes, 2001
This article describes a study in which a series of general education and introductory science courses were assessed using a Likert-scale instrument. As universities across the country have begun to make changes in their science curricula, especially ...
Julie Libarkin
core   +1 more source

Supporting sustained adoption of education innovations: The Designing for Sustained Adoption Assessment Instrument

open access: yes, 2015
BackgroundEvery year, significant effort and resources are expended around the world to develop innovative instructional strategies and materials to improve undergraduate Science, Technology, Engineering, and Mathematics education.
Courtney Stanford   +5 more
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Collaboration among teachers in inclusive special education program classrooms [PDF]

open access: yes, 2016
Collaboration between teachers and special education teachers is a vital factor in ensuring the success of the implementation of the Inclusive Education Programs especially in the teaching and learning aspects.
A. Bakar, A.   +9 more
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

WEBQUEST AN INVIRONMENTAL EDUCATION INSTRUMENT

open access: yesTravessias, 2007
The environmental education must be founded on pedagogical actions based on the study of the relations for creating conditions that contribute to the building of integrated knowledge about the world. One of the possible ways may be the construction of this knowledge by using technologies, which are so present today in the routine of a great part of the
Heerdt, Bettina, Finck Brandt2, Célia
openaire   +2 more sources

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