Results 121 to 130 of about 434,866 (360)

Disabilty in Older Adults with Depression [PDF]

open access: yes, 2005
Depression is a leading cause of disability among older adults which can change the scope of daily life for older adults and threaten their ability to live independently in the community.
Chisholm, Denise
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Unobserved Factors Linking Functional Decline and Depression Among the Oldest Americans [PDF]

open access: yes
This study considers the dependence between functional decline and depression in a nationally representative sample of older Americans from the Survey on Assets and Health Dynamics among the Oldest Old (AHEAD) covering the years from 1993 to 2002 ...
Obrizan, Maksym
core   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Fatigue as a long-term risk factor for limitations in instrumental activities of daily living and/or mobility performance in older adults after 10 years

open access: yesClinical Interventions in Aging, 2016
Sigrid Mueller-Schotte,1–3 Nienke Bleijenberg,1,2,4 Yvonne T van der Schouw,1 Marieke J Schuurmans2,4 1Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands; 2Department for the Chronically Ill ...
Mueller-Schotte S   +3 more
doaj  

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Disability for basic and instrumental activities of daily living in older individuals.

open access: yesPLoS ONE, 2019
AimsTo know the prevalence, associated factors and temporal trends of disabilities for basic and instrumental activities of daily living in older people in Spain from 2009 to 2017.BackgroundDisability in older people is associated with health problems ...
Juan Manuel Carmona-Torres   +5 more
doaj   +1 more source

Kaatumisen pelon seuraukset ikääntyneen arjessa selviämiseen – kuvaileva kirjallisuuskatsaus [PDF]

open access: yes, 2017
Opinnäytetyö tehtiin Vantaan kaupungin tehostetulle kotihoidolle ja se on osa Vantaan kaupungin Vanhusten avopalvelut –hanketta. Opinnäytetyön tarkoituksena oli kuvata kaatumisen pelon seurauksia ikääntyneen fyysiseen toimintakykyyn ja päivittäisiin ...
Kuusisto, Sini, Lampinen, Juulia
core  

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