Results 191 to 200 of about 1,229,939 (300)

A systematic map of methods for assessing societal benefits of Earth science information. [PDF]

Proc Natl Acad Sci U S A
O'Hara CC, Baez-Schon M, Chaplin-Kramer R, Cheng SH, Echeverri A, Galford GL, Gould RK, Mancilla CL, Muldoon MC, Singh GG, Baltezar P, Kuwayama Y, Polasky S, Rodewald AD, Sharp RP, Tennant EJ, Zhao J, Halpern BS.   +17 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Fluorination of Silver Phosphate in Nickel Reaction Vessels for Triple Oxygen Isotope Analysis. [PDF]

Rapid Commun Mass Spectrom
Wostbrock JAG, Yarian D, Chiaravalloti I, Moller SR, Blake RE.   +4 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Transformation to estimate the causal effect in Mendelian randomization study with binary risk factor and outcome. [PDF]

BMC Bioinformatics
Lotfy N.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Can urban renewal improve the self-assessed health of older adults? Evidence from China. [PDF]

Int J Equity Health
Wang X, Yang H, Li Y.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Heart-Cutting Two-Dimensional Liquid Chromatography-Isotope Ratio Mass Spectrometry for Compound-Specific δ¹³C Analysis of Water-Soluble B Vitamins in Complex Supplement Matrices. [PDF]

J Sep Sci
Rockel SP, Martiny J, Jochmann MA, Schmidt TC.   +3 more
europepmc   +1 more source