Results 31 to 40 of about 766 (260)

Realism and Instrumentalism in Philosophical Explanation

Metaphysics, 2019
There is a salient contrast in how theoretical representations are regarded. Some are regarded as revealing the nature of what they represent, as in familiar cases of theoretical identification in physical chemistry where water is represented as hydrogen
Ori Simchen
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

From rhetoric to action, a constitutional analysis of populism

German Law Journal, 2019
The article considers populism not as common ideology but as a common strategy for implementing various distinct ideologies. Constitutional democracy and populist strategy are inherently connected.
Théo Fournier
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Model of Instrumentalism in the Philosophy of Education of Pragmatism and the Neopragmatism Conception

Філософія освіти, 2017
The system-integration aspect of social philosophy and education management is analyzed in the interaction of the concepts of pragmatism and neo-pragmatism instrumentalism in the formation of socio-value orientations. We study the  instrumentalist aspect
Viktor Viktorovych Zinchenko
doaj   +1 more source

Proiectul lui C. Rădulescu-Motru de fundamentare a psihologiei ca știință a naturii

Studii de Istorie a Filosofiei Româneşti, 2023
In his early writings, Rădulescu-Motru acknowledged as a valuable gain the fact that psychology had emancipated itself from the tutelage of metaphysics. However, he believed that this progress could not lead to a scientific psychology unless its outcomes
Mona Mamulea
doaj   +1 more source

Overview of the Instrumentation for the Dark Energy Spectroscopic Instrument

The Astronomical Journal, 2022
Abstract The Dark Energy Spectroscopic Instrument (DESI) embarked on an ambitious 5 yr survey in 2021 May to explore the nature of dark energy with spectroscopic measurements of 40 million galaxies and quasars. DESI will determine precise redshifts and employ the baryon acoustic oscillation method to measure distances from the nearby ...
null DESI Collaboration, B. Abareshi, J. Aguilar, S. Ahlen, Shadab Alam, David M. Alexander, R. Alfarsy, L. Allen, C. Allende Prieto, O. Alves, J. Ameel, E. Armengaud, J. Asorey, Alejandro Aviles, S. Bailey, A. Balaguera-Antolínez, O. Ballester, C. Baltay, A. Bault, S. F. Beltran, B. Benavides, S. BenZvi, A. Berti, R. Besuner, Florian Beutler, D. Bianchi, C. Blake, P. Blanc, R. Blum, A. Bolton, S. Bose, D. Bramall, S. Brieden, A. Brodzeller, D. Brooks, C. Brownewell, E. Buckley-Geer, R. N. Cahn, Z. Cai, R. Canning, R. Capasso, A. Carnero Rosell, P. Carton, R. Casas, F. J. Castander, J. L. Cervantes-Cota, S. Chabanier, E. Chaussidon, C. Chuang, C. Circosta, S. Cole, A. P. Cooper, L. da Costa, M.-C. Cousinou, A. Cuceu, T. M. Davis, K. Dawson, R. de la Cruz-Noriega, A. de la Macorra, A. de Mattia, J. Della Costa, P. Demmer, M. Derwent, A. Dey, B. Dey, G. Dhungana, Z. Ding, C. Dobson, P. Doel, J. Donald-McCann, J. Donaldson, K. Douglass, Y. Duan, P. Dunlop, J. Edelstein, S. Eftekharzadeh, D. J. Eisenstein, M. Enriquez-Vargas, S. Escoffier, M. Evatt, P. Fagrelius, X. Fan, K. Fanning, V. A. Fawcett, S. Ferraro, J. Ereza, B. Flaugher, A. Font-Ribera, J. E. Forero-Romero, C. S. Frenk, S. Fromenteau, B. T. Gänsicke, C. Garcia-Quintero, L. Garrison, E. Gaztañaga, F. Gerardi, H. Gil-Marín, S. Gontcho A Gontcho, Alma X. Gonzalez-Morales, G. Gonzalez-de-Rivera, V. Gonzalez-Perez, C. Gordon, O. Graur, D. Green, C. Grove, D. Gruen, G. Gutierrez, J. Guy, C. Hahn, S. Harris, D. Herrera, Hiram K. Herrera-Alcantar, K. Honscheid, C. Howlett, D. Huterer, V. Iršič, M. Ishak, P. Jelinsky, L. Jiang, J. Jimenez, Y. P. Jing, R. Joyce, E. Jullo, S. Juneau, N. G. Karaçaylı, M. Karamanis, A. Karcher, T. Karim, R. Kehoe, S. Kent, D. Kirkby, T. Kisner, F. Kitaura, S. E. Koposov, A. Kovács, A. Kremin, Alex Krolewski, B. L’Huillier, O. Lahav, A. Lambert, C. Lamman, Ting-Wen Lan, M. Landriau, S. Lane, D. Lang, J. U. Lange, J. Lasker, L. Le Guillou, A. Leauthaud, A. Le Van Suu, Michael E. Levi, T. S. Li, C. Magneville, M. Manera, Christopher J. Manser, B. Marshall, Paul Martini, W. McCollam, P. McDonald, Aaron M. Meisner, J. Mena-Fernández, J. Meneses-Rizo, M. Mezcua, T. Miller, R. Miquel, P. Montero-Camacho, J. Moon, J. Moustakas, E. Mueller, Andrea Muñoz-Gutiérrez, Adam D. Myers, S. Nadathur, J. Najita, L. Napolitano, E. Neilsen, Jeffrey A. Newman, J. D. Nie, Y. Ning, G. Niz, P. Norberg, Hernán E. Noriega, T. O’Brien, A. Obuljen, N. Palanque-Delabrouille, A. Palmese, P. Zhiwei, D. Pappalardo, X. PENG, W. J. Percival, S. Perruchot, R. Pogge, C. Poppett, A. Porredon, F. Prada, J. Prochaska, R. Pucha, A. Pérez-Fernández, I. Pérez-Ràfols, D. Rabinowitz, A. Raichoor, César Ramírez-Pérez, M. Rezaie, A. Rocher, C. Rockosi, A. Roodman, R. Ruggeri, C. G. Sabiu, S. Gaines, K. Said, A. Saintonge, L. Samushia, E. Sanchez, C. Saulder, E. Schaan, D. Schlegel, D. Scholte, A. Secroun, H. Seo, S. Serrano, Ray M. Sharples, Joseph Harry Silber, D. R. Silva, A. Smith, D. Sprayberry, B. Stupak, T. Tan, Gregory Tarlé, Suk Sien Tie, R. Tojeiro, F. Valdes, O. Valenzuela, M. Valluri, M. Vargas-Magaña, L. Verde, M. Walther, B. Wang, M. S. Wang, R. Wechsler, J. Yang, Y. Yu, S. Yuan, Christophe Yèche, H. Zhang, K. Zhang, Cheng Zhao, Rongpu Zhou, Zhimin Zhou, H. Zou, J. Zou, S. Zou, Y. Zu   +250 more
openaire   +12 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Instrumental Variables Regression with Weak Instruments [PDF]

Econometrica, 1997
Summary: This paper develops asymptotic distribution theory for single-equation instrumental variables regression when the partial correlations between the instruments and the endogenous variables are weak, here modeled as local to zero. Asymptotic representations are provided for various statistics, including two-stage least squares (TSLS) and limited
Douglas Staiger, James H. Stock
openaire   +2 more sources