Results 41 to 50 of about 432,273 (390)
Epistemic instrumentalism, permissibility, and reasons for belief [PDF]
, 2018 Epistemic instrumentalists seek to understand the normativity of epistemic norms on the model practical instrumental norms governing the relation between aims and means.
Steglich-Petersen, Asbjørn
core +1 more source
Personal and sub-personal: a defence of Dennett's early distinction [PDF]
, 2000 Since 1969, when Dennett introduced a distinction between personal and sub‐personal levels of explanation, many philosophers have used ‘sub‐personal’ very loosely, and Dennett himself has abandoned a view of the personal level as genuinely autonomous.
Davies M. +18 more
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Instrumentalism about Moral Responsibility Revisited
The Philosophical Quarterly, 2018 I defend an instrumentalist account of moral responsibility and adopt Manuel Vargas’ idea that our responsibility practices are justified by their effects. However, whereas Vargas gives an independent account of morally responsible agency, on my account,
A. Jefferson
semanticscholar +1 more source
The Problem of Unobserved Anomalies [PDF]
, 2018 Scientific antirealism, the view that successful theories are empirically adequate, is untenable in light of the problem of unobserved anomalies that since past scientists could not observe the anomalies that caused the replacement of past theories with ...
Park, Seungbae
core +2 more sources
Critiques of Axiological Realism and Surrealism [PDF]
, 2020 Lyons’s (2003, 2018) axiological realism holds that science pursues true theories. I object that despite its name, it is a variant of scientific antirealism, and is susceptible to all the problems with scientific antirealism.
Park, Seungbae
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
The Necessity of Practical Wisdom
DaimonI defend a generalized developmentalist reading of Aristotle's Nicomachean Ethics by arguing that it allows for a promising solution to the problem of instrumentalism of practical wisdom regarding theoretical wisdom.
Jorge Ignacio Fuentes
doaj +1 more source
Performance Philosophy, 2017 With the emergence, suspicion and social acceptance of ubiquitous communications technology thoroughly plumbed and the digital age already wondering what it is going to rename itself in light of ever more fluid and complex technologies, this paper asks ...
Geraint D'Arcy
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source