Results 61 to 70 of about 432,273 (390)

The problem of political science and practical politics [PDF]

, 2006
Copyright @ 2006 The AuthorsWe reflect on the reasons why there is not a greater and more fruitful relationship between those who seek to understand policy and the political process from academia and those with a similar task in ‘practical politics’.
Almond G., Blunkett D., Cohn J., Commission on the Social Sciences, Dryzek J., Edwards M., Hammersley M., Heyworth G., McGrath C., Rothschild V., Sartori G., Stone D.   +11 more
core   +2 more sources

Beyond Inclusive Conservation: The Value of Pluralism, the Need for Agonism, and the Case for Social Instrumentalism

, 2017
Recent debate within the conservation community about how to define our mission and delineate our objectives has highlighted frictions between conventional (biodiversity centered) conservation and “new” (socio‐economically driven) conservation.
B. S. Matulis, Jessica R. Moyer
semanticscholar   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Proiectul lui C. Rădulescu-Motru de fundamentare a psihologiei ca știință a naturii

Studii de Istorie a Filosofiei Româneşti, 2023
In his early writings, Rădulescu-Motru acknowledged as a valuable gain the fact that psychology had emancipated itself from the tutelage of metaphysics. However, he believed that this progress could not lead to a scientific psychology unless its outcomes
Mona Mamulea
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Instrumental Variables Regression with Weak Instruments [PDF]

Econometrica, 1997
Summary: This paper develops asymptotic distribution theory for single-equation instrumental variables regression when the partial correlations between the instruments and the endogenous variables are weak, here modeled as local to zero. Asymptotic representations are provided for various statistics, including two-stage least squares (TSLS) and limited
Douglas Staiger, James H. Stock
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

An Instrumentalist Account of How to Weigh Epistemic and Practical Reasons for Belief [PDF]

, 2019
When one has both epistemic and practical reasons for or against some belief, how do these reasons combine into an all-things-considered reason for or against that belief?
Skipper, Mattias, Steglich-Petersen, Asbjørn   +1 more
core  

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Pragma-Dialetics Epistemologized: Reply to Lumer

Informal Logic, 2012
I would like to thank Christoph Lumer for his illuminating comments on my paper “The question of truth” published in this journal (Botting 2010) and would like to exercise my right of reply on a few of the issues that he raises.
David Botting
doaj   +3 more sources