Results 91 to 100 of about 18,258 (268)

A generic isotope identification approach for nuclear instrumentation [PDF]

, 2015
Conference Code:121554International audienceIsotope identification is generally done from spectra from high intrinsic resolution such as germanium. A lot of approaches are proposed in the literature.
Sannié, Guillaume, G. Corre, Kondrasovs, Vladimir, Boudergui, K., G. Sannie, V. Kondrasovs, Boudergui, Karim, Sannie, G., Corre, Gwenolé, Corre, G., K. Boudergui   +10 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

DESIGN OF SMART SENSORS FOR DETECTION OF PHYSICAL QUANTITIES [PDF]

, 2010
Microsystems and integrated smart sensors represent a flourishing business thanks to the manifold benefits of these devices with respect to their respective macroscopic counterparts.
DEI, MICHELE
core  

The MISTRAL Instrument and the Characterization of Its Detector Array

Journal of Low Temperature Physics
AbstractThe MIllimeter Sardinia radio Telescope Receiver based on Array of Lumped elements KIDs, MISTRAL, is a cryogenic LEKID camera, operating in the W band ($${77}{-}{103\,\textrm{GHz}}$$ 77 - 103 GHz
Paiella A., Cacciotti F., Isopi G., Barbavara E., Battistelli E. S., de Bernardis P., Capalbo V., Carbone A., Carretti E., Ciccalotti E., Columbro F., Coppolecchia A., Cruciani A., D'Alessandro G., De Petris M., Govoni F., Lamagna L., Levati E., Marongiu P., Mascia A., Masi S., Molinari E., Murgia M., Navarrini A., Novelli A., Occhiuzzi A., Orlati A., Pappalardo E., Pettinari G., Piacentini F., Pisanu T., Poppi S., Porceddu I., Ritacco A., Schirru M. R., Vargiu G.   +35 more
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Advanced instrumentation for superheated liquid detectors in dark matter searches [PDF]

, 2013
Dissertação para obtenção do Grau de Doutor em Engenharia FísicaThe initial goal of the thesis work was to improve the performance of the instrumentation used in the SIMPLE dark matter search.
Costa, Miguel António Felizardo da
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Instrumentation of the very forward region of a linear collider detector

2003 IEEE Nuclear Science Symposium. Conference Record (IEEE Cat. No.03CH37515), 2003
8 pp. (2005).
openaire   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source