Results 51 to 60 of about 1,001,938 (228)
Characterization of a graphite epoxy optical bench during thermal vacuum cycling [PDF]
In-situ monitoring of the Wide-Field/Planetary Camera, a Hubble Space Telescope science instrument, was performed in a vacuum environment to better understand the formation of ice on cooled optical detectors.
Hansen, Patricia A. +3 more
core +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Diagnostics needs for beam-beam studies and optimization
, 2014 During the recent years of LHC operation, we analysed the situation of beam instrumentation and the need to optimize it for beam-beam studies. The most important beam instrumentation devices will be highlighted and modifications or optimizations will be ...
Giachino, R.
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Research Instrument: Instrument Development and Instrument Calibration
Al Hikmah Indonesian Journal of Early Childhood Islamic EducationThe development and calibration of research instruments are crucial components in ensuring the accuracy and reliability of data collection in educational and social sciences. This study addresses the issues surrounding the creation and refinement of research instruments, emphasizing the importance of instrument validity and reliability.
Rizal Firdaus +2 more
openaire +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Instrumentation advances for transonic testing [PDF]
New and improved instrumentation, like new and improved wind tunnels, provide capabilities which stimulate innovative research and discovery. During the past few years there have been a number of instrumentation developments which have aided and abetted ...
Bobbitt, Percy J.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
GRAIL – Grid Access and Instrumentation Tool [PDF]
, 2007 Since the release of Globus Toolkit 4 Web services enrich the world of Grid Computing. They provide methods to develop modular Grid applications which can be parallelized easily.
Gemmeke, H. +3 more
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source