Results 31 to 40 of about 12,003 (292)

Self-Biased Ultralow Power Current-Reused Neural Amplifier With On-Chip Analog Spike Detections

IEEE Access, 2019
An ultralow power 0.6 V neural amplifier with on-chip analog spike detection is presented. A capacitively-coupled instrumentation amplifier (CCIA) with the current-reused and self-biased scheme is proposed to reduce the overall power consumption and to ...
Jongpal Kim, Hyoungho Ko
doaj   +1 more source

Analysis, Simulation, and Development of a Low-Cost Fully Active-Electrode Bioimpedance Measurement Module

Technologies, 2021
A low-cost 1 kHz–400 kHz operating frequency fully-active electrode bioimpedance measurement module, based on Howland current source, is presented in this paper.
Christos Dimas, Vassilis Alimisis, Ioannis Georgakopoulos, Nikolaos Voudoukis, Nikolaos Uzunoglu, Paul P. Sotiriadis   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Design of Low Power and Low Noise Instrumentation Amplifier for Biopotential Acquisition: A Review

IEEE Access
This paper presents a comprehensive review of amplifier design techniques for biomedical sensor implementation focusing on Capacitively Coupled Instrumentation Amplifier (CCIA).
Nahmil Koo
doaj   +1 more source

Twin‐Wire Sensor Networks

Advanced Sensor Research, 2023
A fundamental limit to high‐density sensing is that adding sensors increases the number of wires, pads, and interconnections. This problem is even worse for low‐values resistive or impedance sensors which, for high accuracy, require 4‐wire measurements ...
Sergio Rossi, Nerio Andrés Montoya, Christian Falconi   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Instrumentation Amplifier with Shift Register As a Robot

, 2019
The article presents a concept of designing a Instrumentation Amplifier Circuit supporting efficient and more reliable Amplification processes with some additional features of Amplification (as compared to Operational amplifier and Isolation amplifier ...
Adhikari, Mr. Ganesh, Ganesh Adhikari
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Design of a VDBA-Based Memristor Emulator and Its Application for Bio-Sensing Through Instrument Amplifier

IEEE Open Journal of Nanotechnology
This study describes a VDBA (Voltage Differencing Buffered Amplifier)-based memristor emulator and its use in an instrumentation amplifier for biomedical applications.
Pulak Mondal, Subhasish Banerjee, Mourina Ghosh, Ankur Singh, Santosh Kumar   +4 more
doaj   +1 more source

A Chopper Stabilized Current-Feedback Instrumentation Amplifier for EEG Acquisition Applications

IEEE Access, 2019
A low-noise, low-power, chopper-stabilized, current-feedback instrumentation amplifier (CFIA) for bio-potential signal acquisition applications is presented. The proposed design includes an ac-coupled chopper-stabilized CFIA to reduce 1/f noise.
Chung-Jae Lee, Jong-In Song
doaj   +1 more source