Results 31 to 40 of about 9,973 (258)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Analysis, Simulation, and Development of a Low-Cost Fully Active-Electrode Bioimpedance Measurement Module

open access: yesTechnologies, 2021
A low-cost 1 kHz–400 kHz operating frequency fully-active electrode bioimpedance measurement module, based on Howland current source, is presented in this paper.
Christos Dimas   +5 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Design of a VDBA-Based Memristor Emulator and Its Application for Bio-Sensing Through Instrument Amplifier

open access: yesIEEE Open Journal of Nanotechnology
This study describes a VDBA (Voltage Differencing Buffered Amplifier)-based memristor emulator and its use in an instrumentation amplifier for biomedical applications.
Pulak Mondal   +4 more
doaj   +1 more source

A Chopper Stabilized Current-Feedback Instrumentation Amplifier for EEG Acquisition Applications

open access: yesIEEE Access, 2019
A low-noise, low-power, chopper-stabilized, current-feedback instrumentation amplifier (CFIA) for bio-potential signal acquisition applications is presented. The proposed design includes an ac-coupled chopper-stabilized CFIA to reduce 1/f noise.
Chung-Jae Lee, Jong-In Song
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Noise modeling in a signal conditioning circuit for low power audio application using resistive sensor

open access: yesE3S Web of Conferences, 2016
Piezoresistive sensors convert a physical value into a resistance variation. Often four resistive elements are connected together in a Wheatstone bridge to provide electrical variations of sensors.
Meillère Stéphane   +3 more
doaj   +1 more source

A Micropower CMOS-Instrumentation Amplifier [PDF]

open access: yesIEEE Journal of Solid-State Circuits, 1985
A CMOS switched capacitor instrumentation amplifier is presented. Offset is reduced by an auto-zero technique and effects due to charge injection are attenuated by a special amplifier configuration. The circuit which is realized in a 4-/spl mu/m double poly process has an offset (/spl tau/) of 370 /spl mu/V, an rms input referred integrated noise (0.5 -
M. Degrauwe, E. Vittoz, I. Verbauwhede
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

AN ENHANCED CURRENT-CONVEYOR BASED INSTRUMENTATION AMPLIFIER WITH HIGH CMRR

open access: yesElectrica, 2019
 In this work, a current-mode instrumentation amplifier with common-mode current cancellation is realized using enhanced CCII topology. Detailed CMRR analysis is performed and parameters for maximizing the CMRR are defined.
Uğur ÇİNİ
doaj   +2 more sources

Home - About - Disclaimer - Privacy