Results 41 to 50 of about 12,003 (292)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
E3S Web of Conferences, 2016 Piezoresistive sensors convert a physical value into a resistance variation. Often four resistive elements are connected together in a Wheatstone bridge to provide electrical variations of sensors.
Meillère Stéphane +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
A broadband, high common-mode rejection ratio instrumentation amplifier
, 2021 An operational amplifier based instrumentation amplifier (IA) with a common-mode rejection ratio (CMRR) independent of resistance tolerances is presented in this paper. The CMRR is determined by the operational amplifier characteristics.
van der Horst, Marcel J.
core +1 more source
AN ENHANCED CURRENT-CONVEYOR BASED INSTRUMENTATION AMPLIFIER WITH HIGH CMRR
Electrica, 2019 In this work, a current-mode instrumentation amplifier with common-mode current cancellation is realized using enhanced CCII topology. Detailed CMRR analysis is performed and parameters for maximizing the CMRR are defined.
Uğur ÇİNİ
doaj +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Journal of Low Power Electronics and Applications, 2023 This paper presents a capacitively coupled chopper instrumentation amplifier (CCIA) with ultra-low power consumption and programmable bandwidth for biomedical applications.
Xuan Thanh Pham +2 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
An ultra low-power CMOS instrumentation amplifier for biomedical applications
, 2004 An ultra low-power biopotential instrumentation amplifier, based on the current balancing technique is presented. An internal programmable high-pass filter has been included in the instrumentation amplifier to filter out low-frequency artifacts if ...
LAL, RAKESH, SHARMA, DK, BAGHINI, MS
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source