Results 31 to 40 of about 103,546 (243)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Introducing instrumentation and data acquisition to mechanical engineering students using LabVIEW [PDF]

open access: yes, 2000
For several years, LabVIEW has been used within the Department of Mechanical Engineering at the University of Strathclyde as the basis for introducing the basic concepts and practice of data acquisition, and more generally, instrumentation, to ...
Oldroyd, A, Stickland, M, Strachan, P
core  

Bounded Quantifier Instantiation for Checking Inductive Invariants

open access: yes, 2019
We consider the problem of checking whether a proposed invariant $\varphi$ expressed in first-order logic with quantifier alternation is inductive, i.e. preserved by a piece of code.
Feldman, Yotam M. Y.   +4 more
core   +1 more source

Inherent Limitations of Hybrid Transactional Memory [PDF]

open access: yes, 2015
Several Hybrid Transactional Memory (HyTM) schemes have recently been proposed to complement the fast, but best-effort, nature of Hardware Transactional Memory (HTM) with a slow, reliable software backup.
Alistarh, Dan   +4 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Drilling Parameters Optimization Technology Status and Development Trend

open access: yesShiyou jixie, 2016
With the increasing complex conditions for offshore and underground exploitation,and the continuous development of drilling technology,tools,equipment and instrumentation technology,the corresponding monitoring while drilling technology and computer ...
Sha Linxiu
doaj  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Model-driven performance evaluation for service engineering [PDF]

open access: yes, 2007
Service engineering and service-oriented architecture as an integration and platform technology is a recent approach to software systems integration.
Boskovic, Marko   +2 more
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

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