Results 41 to 50 of about 551,500 (277)

EffectiveSan: Type and Memory Error Detection using Dynamically Typed C/C++

open access: yes, 2018
Low-level programming languages with weak/static type systems, such as C and C++, are vulnerable to errors relating to the misuse of memory at runtime, such as (sub-)object bounds overflows, (re)use-after-free, and type confusion. Such errors account for
Akritidis P.   +10 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Adding traceability to an educational IDE : a thesis presented in partial fulfilment of the requirements for the Master degree in Computer Science at Massey University, Manawatu, New Zealand [PDF]

open access: yes, 2016
High dropout and failure rate in introductory programming courses indicate the need to improve programming comprehension of novice learners. Some of educational tools have successfully used game environments to motivate students. Our approach is based
Sui, Li
core  

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

open access: yesFEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli   +4 more
wiley   +1 more source

A Computer Assisted Program for the Selection of Band Music Relative to the Difficulty Rating of Individual Instruments [PDF]

open access: yes, 1991
The purpose of the study was to develop objective grading tools in the areas of key, range, rhythm/meter, tempo, dynamic and intonation control. Each area was considered separately for 17 different instruments of the band. The study included the development of a computer program capable of permitting a band director to objectively analyze the strengths
openaire   +3 more sources

CONFLLVM: A Compiler for Enforcing Data Confidentiality in Low-Level Code

open access: yes, 2019
We present an instrumenting compiler for enforcing data confidentiality in low-level applications (e.g. those written in C) in the presence of an active adversary.
Bhatu, P.   +8 more
core   +1 more source

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

open access: yesFEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

open access: yesFEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma   +10 more
wiley   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy