Results 41 to 50 of about 1,330,014 (301)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

PENGENDALI KECEPATAN MOTOR DC DENGAN UMPAN MAJU BERBASIS MIKROKONTROLER ATMEGA 16 DENGAN KENDALI HMI VISUAL BASIC 6.0 (The Control Speeds DC with a Forward Based Microcontroler ATMega 16 with Control HMI Visual Basic 6.0) [PDF]

, 2014
Speed control device is a speed measuring instrumentation equipped with a microcontroller and a set of computers. Temperature measuring instrumentation consists of a series DC motor and speed control device.
Masita , Maya
core  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Conflict-driven ASP Solving with External Sources [PDF]

Theor. Pract. Log. Prog. 12:4-5 (2012) 659-679, 2012
Answer Set Programming (ASP) is a well-known problem solving approach based on nonmonotonic logic programs and efficient solvers. To enable access to external information, HEX-programs extend programs with external atoms, which allow for a bidirectional communication between the logic program and external sources of computation (e.g., description logic
arxiv   +1 more source

Introducing instrumentation and data acquisition to mechanical engineering students using LabVIEW [PDF]

, 2000
For several years, LabVIEW has been used within the Department of Mechanical Engineering at the University of Strathclyde as the basis for introducing the basic concepts and practice of data acquisition, and more generally, instrumentation, to ...
Oldroyd, A, Stickland, M, Strachan, P
core  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

A Monitoring Language for Run Time and Post-Mortem Behavior Analysis and Visualization [PDF]

, 2003
UFO is a new implementation of FORMAN, a declarative monitoring language, in which rules are compiled into execution monitors that run on a virtual machine supported by the Alamo monitor architecture.Comment: In M. Ronsse, K.
Auguston, Mikhail, Jeffery, Clinton, Underwood, Scott   +2 more
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Graphical Programming Tools for Electrical Engineering Higher Education

International Journal of Online Engineering (iJOE), 2011
As the engineering education and computer technologies for industry merge, the opportunities for teaching and learning will also expand. In such context, a large number of academic courses that teach electrical engineering concepts have incorporated the ...
E. Lunca, S. Ursache, O. Neacsu
semanticscholar   +1 more source

Transparently Mixing Undo Logs and Software Reversibility for State Recovery in Optimistic PDES [PDF]

, 2015
The rollback operation is a fundamental building block to support the correct execution of a speculative Time Warp-based Parallel Discrete Event Simulation.
Cingolani, Davide, Pellegrini, Alessandro, Quaglia, Francesco   +2 more
core   +1 more source