Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Self-Management Assessment Instruments for Adults with Colorectal Cancer-Related Intestinal Stomas: A Scoping Review. [PDF]
Healthcare (Basel)Zhang J +7 more
europepmc +1 more source
[Texas Instruments Press Releases, August-December 1963]
, 1963 1. Release dated August 1, 1963 announces a variety of appointments to new internal positions. 2. Release dated August 19, 1963 announces a display of 10 operational equipments using semiconductor integrated circuits at the WESCON show.
Texas Instruments Incorporated
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Evaluation of the Application Effectiveness of Defect Management Improvement Models in the Cleaning, Disinfection, and Packaging Management of Surgical Instruments in Central Sterile Supply Departments: A Before-After Study. [PDF]
Risk Manag Healthc PolicyZheng T, Zeng A, Chen Y.
europepmc +1 more source
[Texas Instruments Press Releases, January-April, 1958]
, 1958 Release dated January 2, 1958 announces the appointments of Ernest J. Malovich as supervisor of GSI seismic field parties operating in India and John Utesch as supervisor of several GSI parties in the southeastern US.
Texas Instruments Incorporated
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Scoping Review of Communication Assessment Tools for Family Caregivers: Current Status, Clinical Translation Gaps, and Future Directions. [PDF]
J Multidiscip HealthcXiao J, Tang J, Zhang W, Yang H.
europepmc +1 more source
[Texas Instruments Press Releases, January-July 1955]
, 1955 Release dated January 6, 1955 is in regard to the appointment of Dr. Gordon K. Teal as the head of the TI Research division. The release includes a portrait of Dr. Teal.
Texas Instruments Incorporated
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source