Results 191 to 200 of about 2,398,416 (309)

Psychometric Measures of Instruments of Occupational Performance in Children With Developmental Coordination Disorder: A Systematic Review. [PDF]

Child Care Health Dev
Favilla M, de Souza CB, de Oliveira JA, Rebustini F, Hasue RH.   +4 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Clinical Surface Alteration of Reciprocating Nickel-Titanium Instruments Following Root Canal Preparation and Sterilization: A Three-Dimensional FE-SEM-Based Analysis. [PDF]

Int J Dent
Huynh NH, Le HH, Tran NM, Le HV, Bui HA, Huynh TT, Le HL, Phan PD, Le NT, Tran TL, Pham TK, Nguyen CM, Bui HT, Tran TB, Lam QV, Lam QA, Lam DP, Nguyen TN, Nguyen TT, Pham TH, Do GK, Pham VK, Pham TL, Pham AT.   +23 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

A Decision-Making Framework for Selecting Intimate Partner Violence Measures in Health Research. [PDF]

J Nurs Scholarsh
Williams JR, Burton CW, Grant GG, Hatcher A, Villegas N, Sheffield-Abdullah K.   +5 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Validation of Wound Assessment Instruments Across Brazilian Clinical Contexts: Protocol for a Scoping Review. [PDF]

JMIR Res Protoc
Nunes CAV, Santos ERD, Menezes JDS, Silva MQD, Sasso LSA, Engel AMRPVTC, Rossi GV, Lima CB, Floriano JAS, Cagnazzo PC, Franco RF, Rocha ACS, Rodrigues VAV, Finoto EAV, Rodrigues CDS, Ruiz PBO, Jericó MC, Orlandi FS, Bianchin MA, Spessoto LCF, Oliani AH, Oliani DCMV, Ramos IDS, André JC, Poletti NAA.   +24 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Framing sustainability in Milan's urban policies: new coalitions in a molecular transition. [PDF]

Front Sociol
Bernardi M, Manzano C, Cancellieri A, Tosi S.   +3 more
europepmc   +1 more source