Results 101 to 110 of about 201,620 (299)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Accounting and analysis of financial instruments on the example of JSC "Odessa plant of radial drilling machines»

open access: yes, 2018
Кваліфікаційна робота магістра складається з трьох розділів. Об’єкт дослідження – фінансові інструменти підприємства У роботі розглядаються теоретичні аспекти обліку, аналізу та аудиту операцій з фінансовими інструментами.
Шулянська, Н.Б.
core  

The origin of the Musée des Instruments à vent at la Couture Boussey, a unique case of self-preservation of tradition and craftsmanship

open access: yes, 2019
International audienceLabeled "Museum of France", the Musée des instruments à vent at La Couture-Boussey (Normandy) is located in an historically active woodwinds production area and retains an important collection of instruments made from the 17th ...
Marconi, Emanuele
core   +1 more source

The Discourse of an Instrument, and a Thousand Machines

open access: yes
This paper introduces Qianji (literally meaning in Chinese "A Thousand Machines"), a web-based framework designed for massive distributed audio performance over audience members' own cellular networks. When hundreds of smartphones must function as a synchronized speaker array in a single venue, the congestion and jitter inherent to high-density 4G/5G ...
Duan, Ruilei, Ma, Zhengyang
openaire   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

The Providing of Ultra Precision Conditions for Details’ Pressing Processes on Rotary Machines

open access: yes
The main object of research of details’ pressing processes on rotary machines is focused on how statistical characteristics are established for input and output of different technological operations taking into account the way of machining, that is ...
Mozga, Natālija   +2 more
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

A Meta-Instrument For Interactive, On-The-Fly Machine Learning

open access: yes, 2009
Supervised learning methods have long been used to allow musical interface designers to generate new mappings by example. We propose a method for harnessing machine learning algorithms within a radically interactive paradigm, in which the designer may repeatedly generate examples, train a learner, evaluate outcomes, and modify parameters in real-time ...
Rebecca Fiebrink   +2 more
openaire   +2 more sources

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