Results 81 to 90 of about 228,766 (352)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

[Texas Instruments Press Releases, October-December 1969]

open access: yes, 1969
1. Press release dated October 2, 1963 is in regard to the use of Ti-Guard roofing materials by a sub-contractor, Hahn Roofing And Sheetmetal Contractors of Birmingham, AL to save money on roofing costs. 2.
Texas Instruments Incorporated
core  

Weston Station Voltmeter

open access: yes, 2020
One of the many electrical engineering machines from Weston Electrical Instrument Co. The company was founded by Edward Weston, in 1888, in Newark. Weston was an early competitor of Thomas Edison in electric light but then turned toward innovations in ...
Weston Electrical Instruments
core  

Mathematical Instruments Used in the Military Engineering Academies of the Ottomans

open access: yes, 2018
6th IFToMM International Symposium on the History of Machines and Mechanisms (HMM) -- SEP 26-28, 2018 -- Chinese Acad Sci, Inst Hist Nat Sci, Beijing, PEOPLES R CHINAAt the end of 17th century and during 18th century, in order to train elite cadets who ...
Irem Aslan Seyhan, Seyhan, Irem Asian
core   +1 more source

Diversification instruments for machine-building enterprises

open access: yesIOP Conference Series: Materials Science and Engineering, 2020
Abstract Improving the competitiveness of engineering products, import substitution and increasing high-tech exports are priority government tasks. The development of the high-tech products production is ensured through the diversification of engineering enterprises.
Prilutskaya, M. A.   +3 more
openaire   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Academic Rheology and Industrial Rheology

open access: yesApplied Rheology, 1999
This paper is an attempt to highlight the problems faced by industrial rheologists. The problems are far more complex than subjects of usual academic pursuit.
Nakajima Nobuyuki
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

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