Results 61 to 70 of about 521,852 (304)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Applied Sciences, 2018 Measuring instruments are intended to be intelligent, precise, multi-functional and developing multidirectionally, scientific, and reasonable; the reliable evaluation of measurement uncertainty of precision instruments is also becoming more and more ...
Yinbao Cheng +6 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Instrument subjects are agents or causers [PDF]
, 2007 It has often been noticed that one syntactic argument position can be realized by elements which seem to realize different thematic roles. This is notably the case with the external argument position of verbs of change of state which licenses volitional ...
Alexiadou, Artemis, Schäfer, Florian
core
Reionization and Cosmology with 21 cm Fluctuations [PDF]
, 2009 Measurement of the spatial distribution of neutral hydrogen via the redshifted 21 cm line promises to revolutionize our knowledge of the epoch of reionization and the first galaxies, and may provide a powerful new tool for observational cosmology from ...
J. Stuart B. Wyithe +4 more
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Potential application of bitter gourd (Momordica Charantia) peel as an adsorbent for the removal of total hardness In Kangkar Senangar’s groundwater [PDF]
, 2020 Lately many countries in the world are suffering with the shortage of fresh and clean drinking water as it is a source of life and energy. Rapid pace of industrialization, population expansion, and unplanned urbanization have largely contributed to the ...
Abdul Hamid, Nor Hazren +6 more
core
Principles and promise of Fabry-Perot resonators at terahertz frequencies [PDF]
, 2011 Fabry–Perot resonators have tremendous potential to enhance the sensitivity of spectroscopic systems at terahertz (THz) frequencies. Increasing sensitivity will be of benefit in compensating for the relatively low power of current high resolution ...
Blake, G. A., Braakman, R.
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Virtual Instruments for Detecting Rotor Faults in Induction Motors
Advances in Electrical and Electronic Engineering, 2004 Rotating electrical machines play an important role in the world´s industrial life. Hence there is a demand on their reliable and safe operation. Their faults and failures can lead to excessive downtimes and generate enormous costs in reduced output ...
Lorand Szabo +2 more
doaj