Correlation of tri-ponderal mass index with insulin-like growth factor-I and insulin-like growth factor binding protein-3 in children and adolescents [PDF]
Annals of Pediatric Endocrinology & MetabolismPurpose We aimed to investigate the relationship between the tri-ponderal mass index (TMI), a new indirect measure of fat mass, and insulin-like growth factor (IGF)-I/IGF binding protein (IGFBP)-3.
Iee Ho Choi, Sun-Young Kim, Minsun Kim
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Expression and pathogenesis of insulin-like growth factor-1 and insulin-like growth factor binding protein 3 in a mouse model of ulcerative colitis [PDF]
HeliyonBackground and aim: Insulin-like growth factor-1 may be involved in the epithelial-to-mesenchymal transition process. It can mitigate adverse effects when interacting with insulin-like growth factor binding protein 3.
Weihua Wang +7 more
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The Clinical Values of Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Blood and Thyroid Nodules [PDF]
International Journal of Endocrinology, 2017 Aim. Insulin-like growth factor-1 (IGF-1) is a potent mitogen for many cells. IGF-1 plays a role in the pathogenesis of various tumors with its mutagenic and antiapoptotic properties. The aim of this study was to determine both the serum and intranodular
Ayfer Altas +8 more
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Relationship between growth velocity and change of levels of insulin-like growth factor-1, insulin-like growth factor binding protein-3 and, IGFBP-3 promoter polymorphism during GnRH agonist treatment [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2020 Purpose This study aims to investigate the effect of gonadotropin-releasing hormone agonist (GnRHa) on the growth hormone (GH)-insulin-like growth factor-1 (IGF-1) axis and to evaluate whether -202 A/C IGF binding protein-3 (IGFBP-3) promoter ...
Jun-Hong Park, Il-Tae Hwang, Seung Yang
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Transferrin binds insulin‐like growth factors and affects binding properties of insulin‐like growth factor binding protein‐3 [PDF]
FEBS Letters, 2001 In the circulation, most of the insulin‐like growth factors (IGFs) are bound to a ternary 150 kDa complex with IGF‐binding protein (IGFBP)‐3 and the acid labile subunit. In the current study, we identify transferrin (Tf) by mass spectrometry, and immunoprecipitation as a component of a major IGF‐binding fraction separated from human plasma.
Storch, S. +6 more
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Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Protein-3 in Alzheimer's Disease [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2012 Few large studies have been conducted to assess the relationship between circulating IGF and late-life cognition.The aim of the study was to assess the relationship between IGF-I and IGF binding protein-3 (IGFBP-3) serum levels and cognitive impairment, including Alzheimer's disease (AD).In this multicentric cross-sectional study, 694 elderly subjects (
Duron, Emmanuelle +12 more
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Insulin-like growth factor (IGF)-I and IGF binding proteins axis in diabetes mellitus [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2015 Increasing evidence suggests an important role of the insulin-like growth factor (IGF)-IGF binding protein (IGFBP) axis in the maintenance of normal glucose and lipid metabolism. Significant changes occur in the local IGF-I-IGFBPs environment in response
Min Sun Kim, Dae-Yeol Lee
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Technology in Cancer Research & Treatment, 2020 RNA-binding proteins have been associated with cancer development. The overexpression of a well-known RNA-binding protein, insulin-like growth factor 2 messenger RNA–binding protein 3, has been identified as an indicator of poor prognosis in patients ...
Jing Zhang MS +4 more
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