Results 41 to 50 of about 31,695,425 (269)

MiR-384 Inhibits Malignant Biological Behavior Such as Proliferation and Invasion of Osteosarcoma by Regulating IGFBP3

Technology in Cancer Research & Treatment, 2020
Osteosarcoma is the most common primary malignant bone tumor in the clinic. It is more common in children and adolescents. It has high malignancy, early metastasis rate, rapid disease progression, and high mortality.
Yuelong Tan MM, Linlin Chen MM, Siwei Li MM, He Hao MM, Delong Zhang MM   +4 more
doaj   +1 more source

Role of Insulin-like Growth Factor Binding Protein 3 as a Diagnostic Marker of Growth Hormone in Patients with Acromegaly

Mìžnarodnij Endokrinologìčnij Žurnal, 2013
The paper studied the levels IGFBP-3 in patients with acromegaly, received different therapies. The findings showed that patients with acromegaly after surgical removal of a pituitary tumor, as well as after radiation therapy, the most sensitive ...
A.O. Kholikova
doaj   +1 more source

Short hairpin RNA targeting insulin-like growth factor binding protein-3 restores the bioavailability of insulin-like growth factor-1 in diabetic rats

International Brazilian Journal of Urology, 2016
Purpose To investigate whether intracavernosal injection of short hairpin RNA for IGFBP-3 could improve erectile function in streptozotocin-induced diabetic rats.
Zhang-Yan Zhou, Guang-Jun Zhong, Shao-Ping Cheng, Hui Huang, Jing Wang, Hui Pan, Chang-Mao Liu, Cheng Xing, Ya-Ling Sun, Rong-Hua Liu, Fei-Li   +10 more
doaj   +1 more source

Insulin-Like Growth Factor (IGF)-I and -11 and IGFBinding Proteins-l, -2, and -3 in Children and Adolescents with Diabetes Mellitus: Correlation with Metabolic Control and Height Attainment. [PDF]

, 1995
The putative effects of diabetes and metabolic control on circulating levels of insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) remain controversial.
Past, Roswitha, Kessler, Ulrike, Strasser-Vogel, Brigitte, Hoeflich, Andreas, Blum, Werner F., Meiler, Barbara, Kiess, Wieland   +6 more
core   +1 more source

Serum IGF-1 in patients with rheumatoid arthritis: correlation with disease activity

BMC Research Notes, 2022
Objective Insulin-like growth factor (IGF)-1 participates in modulating immunity and inflammation. Its bioactivity is controlled by six IGF-binding proteins (IGFBP-1 to IGFBP-6).
Hanna Lee, Young Sun Suh, Sang-Il Lee, Yun-Hong Cheon, Mingyo Kim, Hae Sook Noh, Hyun-Ok Kim   +6 more
doaj   +1 more source

QUASI-EXPERIMENTAL EVALUATION OF ZINC SUPPLEMENTATION ON MEAN SERUM INSULIN LIKE GROWTH FACTOR-1 (IGF-1) AND INSULIN LIKE GROWTH FACTOR BINDING PROTEIN-3 (IGFBP-3) LEVELS IN PAKISTANI SHORT STATURED CHILDREN

Pakistan Armed Forces Medical Journal, 2020
Objective: To investigate the influence of supplemental zinc on the levels of insulin like growth factor-1 (IGF-1) and insulin like growth factor binding protein-3 (IGFBP-3) in short statured Pakistani children of 3-6 years of age. Study Design: Quasi-
Sadia Kirn, Amir Ijaz, Safia Fatima, Dilshad Ahmed Khan, Sarmad Nasir   +4 more
doaj   +4 more sources

Insulin-like growth factor 1 and insulin-like growth factor binding protein-3 as predictive biomarkers of depression and migraine in obese women

The Egyptian Journal of Internal Medicine, 2019
Introduction Obesity and its comorbidity, depression and migraine, are highly prevalent conditions and public health problems of enormous scope that are responsible for the significant quality of life impairment and financial cost.
Nearmeen M Rashad, Ahmed F Gomaa, Hanan M Sabry, Amira A Fouad, Shereen M El Shabrawy   +4 more
doaj   +1 more source

Malnutrition in children associated with low insulin-like growth factor binding protein-3 (IGFBP-3) levels

Gaceta Sanitaria, 2021
Objective: This study aimed to compare serum levels of Insulin-like Growth Factor Binding Protein-3 in children with malnutrition and good nutritional status.
Dwi Ayu Rahmawati, Aminuddin Aminuddin, Firdaus Hamid, Prihantono Prihantono, Burhanuddin Bahar, Veni Hadju   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source