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Insulin like growth factor - insulin like growth factor binding protein family in osteoporosis: mechanistic and clinical insights. [PDF]

open access: yesAnn Med
Introduction The imbalance between osteoblasts and osteoclasts is central to osteoporosis.Insulin like growth factor (IGF) has protective effects on bone. As an IGF-binding protein, the role of IGFBP in bone has also begun to come into the public’s view.
Wang X, Zhang J, Luo Z.
europepmc   +2 more sources

Risk prognosis correlation of insulin-like growth factor binding protein-3 and insulin-like growth factor-1 in uterine fibroids. [PDF]

open access: yesJ Med Biochem
Background: To explore the relationships between the levels of serum insulin-like growth factor binding protein-3 (IGFBP-3) and insulin-like growth factor 1 (IGF-1) and immune factors, as well as the prognosis of patients with uterine fibroids.
Lin T, Qian K, Chen Y, Li M, Zhang Z.
europepmc   +2 more sources

The multifaceted role of insulin-like growth factor binding protein 7. [PDF]

open access: yesFront Cell Dev Biol
Insulin-like growth factor binding protein 7 (IGFBP7) serves as a crucial extracellular matrix protein, exerting pivotal roles in both physiological and pathological processes.
Chen L, Hui L, Li J.
europepmc   +2 more sources

Expression of insulin-like growth factor binding protein-3 in HELLP syndrome. [PDF]

open access: yesBMC Pregnancy Childbirth, 2023
Objective To investigate the expression of insulin-like growth factor binding protein-3(IGFBP-3) in HELLP syndrome and its possible role in the pathogenesis of this disease. Methods 1) 87 subjects were enrolled, including 29 patients with HELLP syndrome,
Wei L, Liping Z, Suya K.
europepmc   +2 more sources

Insulin-Like Growth Factor Binding Protein, Acid-Labile Subunit Serum Level During the Acute and Convalescent Stage of SARS-CoV-2 Infection Depicted in a Longitudinal Study of 72 Patients During the First Wave of Pandemic. [PDF]

open access: yesJ Multidiscip Healthc
Hossam Gad,1,* Mohamed A Mahmoud,2,* Mohamed Antar,1 Ahmed Sayed Ahmed,2 Krzysztof Laudanski3 1Department of Anesthesiology and Perioperative Care, Mayo Clinic, Rochester, MN, USA; 2Division Pulmonary and Critical Care, Mayo Clinic ...
Gad H   +4 more
europepmc   +2 more sources

Dynamic changes in insulin-like growth factor binding protein expression occur between embryonic and early post-hatch development in broiler chickens. [PDF]

open access: yesPoult Sci
: Somatotropic gene expression has been altered by genetic selection, and developmental changes in insulin-like growth factor (IGF) and IGF binding protein (IGFBP) expression may contribute to rapid growth and muscle accretion in commercial broilers. The
Vaccaro LA   +5 more
europepmc   +2 more sources

Correlation of Insulin Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein with LH, FSH and Testosterone in Iraqi Children with Growth Hormone Deficiency

open access: yesIraqi Journal of Chemical and Petroleum Engineering, 2023
Insulin like growth factor-1 has metabolic and growth-related roles all over the body and is strongly associated and regulated by growth hormone. It is produced by almost any type of tissue, especially the liver.
Athraa F. Hasan   +2 more
doaj   +1 more source

The Aberrant Expression of MicroRNA-125a-5p/IGF2BP3 Axis in Advanced Gastric Cancer and Its Clinical Relevance

open access: yesTechnology in Cancer Research & Treatment, 2020
RNA-binding proteins have been associated with cancer development. The overexpression of a well-known RNA-binding protein, insulin-like growth factor 2 messenger RNA–binding protein 3, has been identified as an indicator of poor prognosis in patients ...
Jing Zhang MS   +4 more
doaj   +1 more source

Insulin-like growth factor (IGF)-I and IGF binding proteins axis in diabetes mellitus [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2015
Increasing evidence suggests an important role of the insulin-like growth factor (IGF)-IGF binding protein (IGFBP) axis in the maintenance of normal glucose and lipid metabolism. Significant changes occur in the local IGF-I-IGFBPs environment in response
Min Sun Kim, Dae-Yeol Lee
doaj   +1 more source

Animal insulin-like growth factor binding proteins and their biological functions

open access: yesVeterinární Medicína, 2002
Insulin-like growth factor (IGF-I, IGF-II) action is influenced by until today known eight forms of insulin-like growth factor binding proteins (IGFBPs).
Z. Kostecká, J. Blahovec
doaj   +1 more source

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