Results 1 to 10 of about 7,031,181 (311)
Single Cell Center of Mass for the Analysis of BMP Receptor Heterodimers Distributions
Journal of Imaging, 2021 At the plasma membrane, transmembrane receptors are at the interface between cells and their environment. They allow sensing and transduction of chemical and mechanical extracellular signals.
Hendrik Boog +2 more
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Yap1-2 Isoform Is the Primary Mediator in TGF-β1 Induced EMT in Pancreatic Cancer
Frontiers in Oncology, 2021 Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive human malignancy and intrinsically resistant to conventional therapies. YAP1, as a key downstream effector of the Hippo pathway, plays an important role in tumorigenesis including PDAC ...
Chao Gao +14 more
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Cancer Medicine, 2023 Epithelium‐specific ETS transcription factor 1 (ESE1) has been implicated in epithelial homeostasis, inflammation, as well as tumorigenesis, and cancer progression.
Hui‐Jing Xu +12 more
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FGF10 and Lipofibroblasts in Lung Homeostasis and Disease: Insights Gained From the Adipocytes
Frontiers in Cell and Developmental Biology, 2021 Adipocytes not only function as energy depots but also secrete numerous adipokines that regulate multiple metabolic processes, including lipid homeostasis.
Yu-Qing Lv +8 more
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FGF1 alleviates LPS-induced acute lung injury via suppression of inflammation and oxidative stress
Molecular Medicine, 2022 Background Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS), are devastating clinical disorders with high mortality, and for which more effective therapies are urgently needed.
Qhaweni Dhlamini +11 more
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Cells, 2022 Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease with dire consequences and in urgent need of improved therapies. Compelling evidence indicates that damage or dysfunction of AT2s is of central importance in the development ...
Yu-Qing Lv +12 more
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FGF Signaling Pathway: A Key Regulator of Stem Cell Pluripotency
Frontiers in Cell and Developmental Biology, 2020 Pluripotent stem cells (PSCs) isolated in vitro from embryonic stem cells (ESCs), induced PSC (iPSC) and also post-implantation epiblast-derived stem cells (EpiSCs) are known for their two unique characteristics: the ability to give rise to all somatic ...
Majid Mossahebi-Mohammadi +4 more
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An FGFR/AKT/SOX2 Signaling Axis Controls Pancreatic Cancer Stemness
Frontiers in Cell and Developmental Biology, 2020 Cancer stemness is associated with high malignancy and low differentiation, as well as therapeutic resistance of tumors including pancreatic ductal adenocarcinoma (PDAC). Fibroblast growth factors (FGFs) exert pleiotropic effects on a variety of cellular
Mei-Yu Quan +16 more
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Haemopoietic growth factors [PDF]
Postgraduate Medical Journal, 1997 Summary Haemopoietic growth factors are involved in the production of the various blood cells from progenitors in the bone marrow, making them useful in a range of clinical situations. The genes for several of them have been cloned and their production engineered by recombinant technology, making them widely available.
N J, Ketley, A C, Newland
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Journal of Indian Academy of Oral Medicine and Radiology, 2023 Background: Mast cells are thought to be complex, multifaceted cells that are important for tumor angiogenesis and immunopathology. Mast cell buildup at the periphery of the tumor and their production of strong pro- and angiogenic chemicals may be signs ...
Arpita Kabiraj +5 more
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