Results 41 to 50 of about 11,216,259 (234)

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

The Molecular Mechanism of Craniofacial Cartilage Deformity Induced by High Glucose in Zebrafish

Current Issues in Molecular Biology
Gestational diabetes mellitus (GDM), a prevalent metabolic disorder in pregnancy, induces maternal hyperglycemia and elevates fetal malformation risks, particularly in craniofacial development.
Xiaomei Chen, Yong Huang, Xin Yang, Huiqiang Lu, Jian Yang   +4 more
doaj   +1 more source

Periodontal Regeneration of Intrabony Defects in Animal Models Using Biologic Modifiers: A Systematic Review and Meta-analysis

Journal of Mazandaran University of Medical Sciences, 2021
Background and purpose: The ultimate goal in periodontal treatment is to achieve a functional and anatomical regeneration of lost tissues. Due to the promising outcomes of biologic modifiers in regenerative therapies, this systematic review aimed at ...
Zeynab Farimani, Mojgan Paknejad, Mahboubeh Bohlouli, Navid Yousefi, Neda Izadi, Soolmaz Akbari   +5 more
doaj  

Pertumbuhan Bibit Kakao (Theobroma cacao L.) pada Berbagai Jenis Klon dan Jenis Pupuk Kandang

Jurnal Agro Industri Perkebunan, 2021
Several factors that affect production of cocoa (Theobroma cacao L.), one of which is the quality of seedlings. The quality of seedlings is affected by the type of clones and the composition of the planting media.
Leni Sri Widyastuti, Yonathan Parapasan, Made Same   +2 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Evidence that metformin promotes fibrosis resolution via activating alveolar epithelial stem cells and FGFR2b signaling

Acta Pharmaceutica Sinica B
Idiopathic pulmonary fibrosis (IPF) is a progressive disease lacking effective therapy. Metformin, an antidiabetic medication, has shown promising therapeutic properties in preclinical fibrosis models; however, its precise cellular targets and associated
Yuqing Lv, Yanxia Zhang, Xueli Guo, Baiqi He, Haibo Xu, Ming Xu, Lihui Zou, Handeng Lyu, Jin Wu, Pingping Zeng, Saverio Bellusci, Xuru Jin, Chengshui Chen, Young-Chang Cho, Xiaokun Li, Jin-San Zhang   +15 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Exposure to propylparaben induces craniofacial bone developmental toxicity through ROS-induced oxidative stress and apoptosis in zebrafish (Danio rerio) embryos

Ecotoxicology and Environmental Safety
Propylparaben (PrP) is an extensively utilized antimicrobial preservative in food industry, cosmetics, personal care products, and pharmaceuticals. Nevertheless, the toxicological effects of PrP on animals are still not well characterized. In this study,
Runhao Zhu, Yong Huang, Xinyue Chang, Xiaomei Chen, Hanyi Zhu, Yujie Yan, Siling Liu, Huiqiang Lu, Jian Yang   +8 more
doaj   +1 more source

Autocrine regulation of asthmatic airway inflammation: role of airway smooth muscle

Respiratory Research, 2001
Chronic airway inflammation is one of the main features of asthma. Release of mediators from infiltrating inflammatory cells in the airway mucosa has been proposed to contribute directly or indirectly to changes in airway structure and function.
McKay Sue, Sharma Hari S
doaj   +1 more source