Results 41 to 50 of about 7,031,181 (311)

Epidermal Growth Factor

Journal of Investigative Dermatology, 1972
During the course of the studies on the nerve growth factor of the submaxillary gland of the male mouse (1), it was observed that extracts of these glands, when injected into newborn mice, caused precocious opening of the eyelid and eruption of the incisors. A polypeptide responsible for this effect has been isolated (2).
openaire   +3 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Evidence that metformin promotes fibrosis resolution via activating alveolar epithelial stem cells and FGFR2b signaling

Acta Pharmaceutica Sinica B
Idiopathic pulmonary fibrosis (IPF) is a progressive disease lacking effective therapy. Metformin, an antidiabetic medication, has shown promising therapeutic properties in preclinical fibrosis models; however, its precise cellular targets and associated
Yuqing Lv, Yanxia Zhang, Xueli Guo, Baiqi He, Haibo Xu, Ming Xu, Lihui Zou, Handeng Lyu, Jin Wu, Pingping Zeng, Saverio Bellusci, Xuru Jin, Chengshui Chen, Young-Chang Cho, Xiaokun Li, Jin-San Zhang   +15 more
doaj   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

Exposure to propylparaben induces craniofacial bone developmental toxicity through ROS-induced oxidative stress and apoptosis in zebrafish (Danio rerio) embryos

Ecotoxicology and Environmental Safety
Propylparaben (PrP) is an extensively utilized antimicrobial preservative in food industry, cosmetics, personal care products, and pharmaceuticals. Nevertheless, the toxicological effects of PrP on animals are still not well characterized. In this study,
Runhao Zhu, Yong Huang, Xinyue Chang, Xiaomei Chen, Hanyi Zhu, Yujie Yan, Siling Liu, Huiqiang Lu, Jian Yang   +8 more
doaj   +1 more source

Autocrine regulation of asthmatic airway inflammation: role of airway smooth muscle

Respiratory Research, 2001
Chronic airway inflammation is one of the main features of asthma. Release of mediators from infiltrating inflammatory cells in the airway mucosa has been proposed to contribute directly or indirectly to changes in airway structure and function.
McKay Sue, Sharma Hari S
doaj   +1 more source

Anti epidermal growth factor receptor therapy in small bowel adenocarcinoma [PDF]

, 2018
Rationale:Small bowel adenocarcinoma (SBA) is an uncommon gastrointestinal cancer, thus limited data about treatment for advanced disease are available.
Anselmi, Elisabetta, Falcone, Rosa, Filetti, Marco, Marchetti, Paolo, Roberto, Michela   +4 more
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Comparison of the Interactions of Different Growth Factors and Glycosaminoglycans

Molecules, 2019
Most growth factors are naturally occurring proteins, which are signaling molecules implicated in cellular multiple functions such as proliferation, migration and differentiation under patho/physiological conditions by interacting with cell surface ...
Fuming Zhang, Langhong Zheng, Shuihong Cheng, Yanfei Peng, Li Fu, Xing Zhang, Robert J. Linhardt   +6 more
doaj   +1 more source

Effect of Acellular Amnion With Increased TGF-β and bFGF Levels on the Biological Behavior of Tenocytes

Frontiers in Bioengineering and Biotechnology, 2020
The human amniotic membrane has been a subject for clinical and basic research for nearly 100 years, but weak rejection has been reported. The purpose of this research is to remove the cellular components of the amnion for eliminating its immune-inducing
Rongli Sang, Yuanyuan Liu, Lingyu Kong, Ligang Qian, Chunjie Liu   +4 more
doaj   +1 more source