Results 251 to 260 of about 90,099 (312)

Stability of Insulin Lispro in Insulin Infusion Systems

Diabetes Care, 1997
OBJECTIVE To test stability of insulin lispro in two insulin infusion systems over 48 h. RESEARCH DESIGN AND METHODS We used reverse-phase and size-exclusion high-performance liquid chromatography (HPLC) to determine the purity, potency, and degree ...
W D, Lougheed, B, Zinman, T R, Strack, L J, Janis, A B, Weymouth, E A, Bernstein, A M, Korbas, B H, Frank   +7 more
openaire   +2 more sources

Automatic Regulation of Basal Insulin Infusion in a Personalized Insulin Therapy System

Biomedical Engineering, 2021
A method and a system for automatic regulation of the basal insulin administration rate for maintenance of glycemia in the target range are proposed. The method is based on proportional regulation of the infusion rate using feedback. It suspends the insulin delivery when the glucose level falls below a threshold value. According to the modeling results,
E. L. Litinskaia, K. V. Pozhar, E. A. Polyakova   +2 more
openaire   +1 more source

Newer Insulin Delivery Systems: Continuous Subcutaneous Insulin Infusion

1979
The quest for new methods of administering insulin has been primarily stimulated by the practical difficulty of achieving long periods of strict blood glucose and major intermediary metabolites control with conventional insulin injection therapy.
J C, Pickup, H, Keen, J A, Parsons, K G, Alberti   +3 more
openaire   +2 more sources

Comparison of peripheral and portal routes of insulin infusion by a computer-controlled insulin infusion system (artificial endocrine pancreas)

Diabetes, 1976
This study was undertaken to determine the different consequences of portal and peripheral routes of insulin administration by the artificial endocrine pancreas. Intraportal glucose was infused (10 mg./min./kg. for 60 minutes) in anesthetized normal and pancreatectomized dogs while blood glucose concentrations were monitored continuously.
C K, Botz, B S, Leibel, W, Zingg, R E, Gander, A M, Albisser   +4 more
openaire   +2 more sources

Insulin Levels After Portal and Systemic Insulin Infusion Differ in a Dose-Dependent Fashion

Hormone and Metabolic Research, 1998
The role of the liver in the regulation of systemic insulin levels is not well understood. The reported extraction rates vary between 0 to 85%, and extraction of a constant fraction of 50% of the portally delivered insulin is generally assumed. In the present study, we have investigated the role of the liver in the regulation of systemic insulin levels
de Vos, P., de Haan, Bart, Vegter, D., Hillebrands, J.L., Strubbe, J.H., Bruggink, Jan, Schilfgaarde, R. van   +6 more
openaire   +3 more sources

Continuous subcutaneous insulin infusion systems

Postgraduate Medicine, 1983
Although continuous subcutaneous insulin infusion (CSII) is not presently the most feasible method of insulin delivery for most type I diabetic patients, unquestionably it is a major therapeutic advance in recent efforts to normalize blood glucose levels in such patients.
openaire   +2 more sources

Control of Insulin-Dependent Diabetes with Portable Miniaturized Infusion Systems

Diabetes Care, 1980
A method of insulin therapy that appears to achieve better control of diabetes than present conventional methods is the use of insulin infusion devices — either glucose-controlled feedback (closed-loop) systems or the preprogrammed (open-loop) infusion pump.
K D, Hepp, R, Renner, K, Piwernetz, H, Mehnert   +3 more
openaire   +2 more sources

Programming of an open-loop system for I.V. insulin infusion in insulin-dependent diabetes

Acta Diabetologica Latina, 1980
The blood glucose of 10 stable unstressed uncomplicated insulin-dependent diabetics (age: 39 ± 4 years; duration of diabetes: 11 ± 1 years) was controlled by a preprogrammed open-loop system of i.v. insulin infusion during two randomized consecutive days. Individual constant basal insulin rates were determined by adapting the rate of the pump to obtain
J, Mirouze, J L, Selam, T C, Pham, D, Chenon   +3 more
openaire   +2 more sources