Results 231 to 240 of about 9,494,626 (300)

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

Advanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin   +7 more
wiley   +1 more source

A consensus statement on a National Competency Framework for training and assessment of knowledge and skills in diabetes technologies, including hybrid closed loop (HCL), insulin pump systems, and continuous glucose monitoring (CGM) devices. [PDF]

Diabet Med
Richardson E, Stribling B, Ridgeway J, Kitching-Davis C, Willcocks L, Heggs L, Wakefield H, Gallen G, Jolley A, Bareford K, Williams A, Farrow D, Fletcher-Salt T, Hicks D, Higgins J, Jordan L, Kelly B, Metcalf-O'Shea C, Turner M, Walden E, Walker A, Choudhary P.   +21 more
europepmc   +1 more source

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

Effect of diet macronutrient content on the cardiometabolic response to weight loss: A randomized clinical trial. [PDF]

Cell Metab
Petersen MC, Smith GI, Farabi SS, Palacios HH, Shankaran M, Hellerstein MK, Patterson BW, Klein S.   +7 more
europepmc   +1 more source

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

Advanced Science, EarlyView.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su, Zhiyan Gong, Jiao Mu, Lili Huang, Pengfei Yang, Chenli Zhang, Lingshan Zhao, Liling Yang, Jun Deng, Xiaohui Liao   +9 more
wiley   +1 more source

How Nurses Maintain High-Risk Medication Safety in Paediatric Intensive Care. [PDF]

Nurs Crit Care
Huang M, Lv M, Huang J, Lin Y.
europepmc   +1 more source

Medical code embeddings from claims-based co-occurrences: a unified semantic space for ICD-10 diagnoses and ATC medications. [PDF]

J Am Med Inform Assoc
Faujour C, Bouée S, Emery C, Jannot AS.
europepmc   +1 more source

Efficacy and Safety of Tubeless Hybrid Closed-Loop Systems in Type 1 Diabetes: A Meta-Analysis of Randomized Controlled Trials. [PDF]

Diabetes Obes Metab
Lei M, Lin Q, Zhou Y, Ni Y, Lin Z, Ling P, Dai Z, Tang J, Yan J.   +8 more
europepmc   +1 more source

Mitochondrial Proteostasis Links Diabetes and Sarcopenia: Cross-Scale Convergence from Experimental Models to Human Multi-Omics. [PDF]

Diabetes Metab J
Wei S, Shin S, Ryu D, Oh CM.
europepmc   +1 more source

Translational Development of Physiologic IGF-1 Replacement for the Prevention of Bronchopulmonary Dysplasia. [PDF]

Biomedicines
Niklas V, Barton N.
europepmc   +1 more source