Results 251 to 260 of about 39,968 (304)

Cannula Occlusion With Use of Insulin Lispro and Insulin Infusion System

Diabetes Care, 1998
AW David Wright, J Alick Little
exaly   +2 more sources

Continuous subcutaneous insulin infusion in diabetes: patient populations, safety, efficacy, and pharmacoeconomics

Diabetes/Metabolism Research and Reviews, 2016
International audienceThe level of glycaemic control necessary to achieve optimal short-term and long-term outcomes in subjects with type 1 diabetes mellitus (T1DM) typically requires intensified insulin therapy using multiple daily injections or ...
Paolo Pozzilli, Tadej Battelino, Thomas Danne   +2 more
exaly   +2 more sources

Stability of Insulin Lispro in Insulin Infusion Systems

Diabetes Care, 1997
OBJECTIVE To test stability of insulin lispro in two insulin infusion systems over 48 h. RESEARCH DESIGN AND METHODS We used reverse-phase and size-exclusion high-performance liquid chromatography (HPLC) to determine the purity, potency, and degree ...
W D, Lougheed, B, Zinman, T R, Strack, L J, Janis, A B, Weymouth, E A, Bernstein, A M, Korbas, B H, Frank   +7 more
openaire   +2 more sources

Automatic Regulation of Basal Insulin Infusion in a Personalized Insulin Therapy System

Biomedical Engineering, 2021
A method and a system for automatic regulation of the basal insulin administration rate for maintenance of glycemia in the target range are proposed. The method is based on proportional regulation of the infusion rate using feedback. It suspends the insulin delivery when the glucose level falls below a threshold value. According to the modeling results,
E. L. Litinskaia, K. V. Pozhar, E. A. Polyakova   +2 more
openaire   +1 more source

Newer Insulin Delivery Systems: Continuous Subcutaneous Insulin Infusion

1979
The quest for new methods of administering insulin has been primarily stimulated by the practical difficulty of achieving long periods of strict blood glucose and major intermediary metabolites control with conventional insulin injection therapy.
J C, Pickup, H, Keen, J A, Parsons, K G, Alberti   +3 more
openaire   +2 more sources

Comparison of peripheral and portal routes of insulin infusion by a computer-controlled insulin infusion system (artificial endocrine pancreas)

Diabetes, 1976
This study was undertaken to determine the different consequences of portal and peripheral routes of insulin administration by the artificial endocrine pancreas. Intraportal glucose was infused (10 mg./min./kg. for 60 minutes) in anesthetized normal and pancreatectomized dogs while blood glucose concentrations were monitored continuously.
C K, Botz, B S, Leibel, W, Zingg, R E, Gander, A M, Albisser   +4 more
openaire   +2 more sources

Programming of an open-loop system for I.V. insulin infusion in insulin-dependent diabetes

Acta Diabetologica Latina, 1980
The blood glucose of 10 stable unstressed uncomplicated insulin-dependent diabetics (age: 39 ± 4 years; duration of diabetes: 11 ± 1 years) was controlled by a preprogrammed open-loop system of i.v. insulin infusion during two randomized consecutive days. Individual constant basal insulin rates were determined by adapting the rate of the pump to obtain
J, Mirouze, J L, Selam, T C, Pham, D, Chenon   +3 more
openaire   +2 more sources

Insulin Levels After Portal and Systemic Insulin Infusion Differ in a Dose-Dependent Fashion

Hormone and Metabolic Research, 1998
The role of the liver in the regulation of systemic insulin levels is not well understood. The reported extraction rates vary between 0 to 85%, and extraction of a constant fraction of 50% of the portally delivered insulin is generally assumed. In the present study, we have investigated the role of the liver in the regulation of systemic insulin levels
de Vos, P., de Haan, Bart, Vegter, D., Hillebrands, J.L., Strubbe, J.H., Bruggink, Jan, Schilfgaarde, R. van   +6 more
openaire   +3 more sources

Specification and simulation of behavior of the Continuous Infusion Insulin Pump system

Bio-Medical Materials and Engineering, 2014
Continuous Infusion Insulin Pump (CIIP) system is responsible for monitoring diabetic blood sugar. In this paper, we aim to specify and simulate the CIIP software behavior. To this end, we first: (1) presented a model consisting of the CIIP system behavior in response to its environment (diabetic) behavior and (2) we formally defined the safety ...
Seyed Morteza, Babamir, Mehdi Borhani, Dehkordi   +1 more
openaire   +2 more sources

Design of A Polymeric Insulin Infusion System For Blood Glucose Control

2007 American Control Conference, 2007
A polymeric device that is able to reversibly swell and deswell in response to an environmental stimulus has great potential in the application of tight blood glucose control without the necessity of process equipment. The release of insulin from spherical particles has been simulated to show the effects of the number of particles injected, the mass ...
Terry G. Farmer, Nicholas A. Peppas, Thomas F. Edgar   +2 more
openaire   +1 more source