Results 211 to 220 of about 87,132 (309)

Real-world glycemic outcomes of a tubeless automated insulin delivery system: a single-center observational study in Italy. [PDF]

Front Endocrinol (Lausanne)
Angelino S, Maiorino MI, Petrizzo M, Di Martino N, Caruso P, Carbone C, Pontillo A, Maio A, Longo M, Scappaticcio L, Bellastella G, Esposito K.   +11 more
europepmc   +1 more source

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

Advanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan, Xuelin Wang, Zhongyao Chen, Shuo Wang, Weining Gao, Ziyi Chen, Runyang Li, Cheng Hao, Lei Zhang, Qiongqiong Zhang, Ke Zhang, Mei Yu, Qian Liu, Jingxuan Wang, Huiping Li, Simpkins Fiona, Jing Liu, Qiang Liu, Peng Liu, Yawei Hu   +19 more
wiley   +1 more source

A retrospective observational study evaluating the safety and effectiveness of commercially available automated insulin delivery systems in people with type 1 diabetes and gastroparesis. [PDF]

Diabetes Obes Metab
Tan RJL, Ahuja A, Shrestha A, Gallen G, Stotesbury B, Cheah Y, Mustafa OG, Whyte MB, Croos J, Shooshtarian A, Hayee BH, Stadler M.   +11 more
europepmc   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Cybersecurity in connected medical devices: a policy agenda for the NHS. [PDF]

NPJ Digit Med
Toparti O, Rajput K, Darzi A, Ghafur S.
europepmc   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

Successful rapid desensitization to multiple insulin preparations in an adult with type 1 diabetes: a case report and literature review. [PDF]

Front Endocrinol (Lausanne)
Chen Y, Zhu W, Chen G, Yao J.
europepmc   +1 more source

NSUN5 Attenuates Renal Injury and Ferroptosis in Hyperuricaemic Nephropathy Through YBX2‐Dependent Stabilisation of SCD1 m5C Methylation

Advanced Science, EarlyView.
NSUN5 is downregulated in hyperuricaemic nephropathy. Overexpression of NSUN5 enhances the stability of SCD1 mRNA through the m5C reader YBX2, ultimately inhibiting ferroptosis in renal tubular epithelial cells. Additionally, this axis suppresses the NF‐κB signaling pathway to alleviate inflammation and upregulates ABCG2 to promote uric acid excretion,
Xiu‐xiu Song, Xiao‐guo Suo, Yue Yu, Kuo Zhang, Chen‐ao Li, Jie Wang, Hui‐xia Xu, Si‐yu Niu, Dong‐xue Lv, Zi‐hao He, Feng‐he Li, Xiao‐ming Meng, Juan Jin   +12 more
wiley   +1 more source

Use of Teplizumab to Modulate Stage 2 Type 1 Diabetes in Two Individuals With Autoimmune Polyendocrine Syndrome 1. [PDF]

Diabetes Care
Wilson CS, Falk A, Williams JM, Hilmes M, Ross J, LeStourgeon L, Haller MJ, Drawdy M, Pechacek J, Webb T, Diaz-Thomas A, Russell WE, Gregory JM, Virostko J, Lionakis MS, Moore DJ.   +15 more
europepmc   +1 more source

Clinical science and care incorporating the development of a European Platform for Clinical Research in Diabetes (EPCRD) [PDF]

, 2010
Danne, T., Diamant, M., Hood, G., Kautzky-Willer, A., Kerr, David, Mitrakou, A., Nilsson, P.A., Nolan, J. J, Pacini, G.   +8 more
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