Results 51 to 60 of about 3,242,962 (243)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

What are the experiences of children aged 2–12 years with type 1 diabetes, adolescents aged 13–17 years with type 1 diabetes, and that of their parents when making the transition to insulin pump therapy?

, 2009
Whilst researchers have identified an improvement in quality of life for families using insulin pump therapy there is little information about the experiences of children and/or adolescents and their parents when making the transition to insulin pump ...
Pay, Roslyn
core   +1 more source

Effectiveness of sensor-augmented insulin-pump therapy in type 1 diabetes [PDF]

, 2010
BACKGROUND: Recently developed technologies for the treatment of type 1 diabetes mellitus include a variety of pumps and pumps with glucose sensors. METHODS: In this 1-year, multicenter, randomized, controlled trial, we compared the efficacy of sensor ...
Wood, M.A., Tamborlane, W.V., Buse, J.B., Joyce, C., Perkins, B.A., Willi, S.M., Peoples, T., Davis, S.N., Ahmann, A., Dailey, G., Bergenstal, R.M., Welsh, J.B.   +11 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Insulin Allergy to Detemir Followed by Rapid Onset of Diabetic Ketoacidosis: A Case Report and Literature Review

Frontiers in Endocrinology, 2022
The management of diabetes mellitus in an insulin-dependent patient is challenging in the setting of concomitant antibody-mediated-insulin hypersensitivity.
Chong Boon Teo, Pek Yan Tan, Shan Xian Lee, Joan Khoo, Jun Guan Tan, Su Fen Ang, Sze Hwa Tan, Tunn Lin Tay, Eberta Tan, Su Chi Lim, Su Chi Lim, Bernhard O. Boehm, Bernhard O. Boehm, Bernhard O. Boehm, Wann Jia Loh   +14 more
doaj   +1 more source

Insulin Pump School: Back to the Basics of Pump Therapy [PDF]

, 2012
The Longstreet Clinic (TLC), P.C. is a regional multidisciplinary physician practice. The Internal Medicine (IM) and Family Medicine (FM) departments are located in Gainesville and Oakwood (Hall County), Georgia.
Williams, Cheryl, Reece, Sara Wilson
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The education of patients in prandial insulin dosing related to the structure of bolus calculators [PDF]

Pediatric Endocrinology, Diabetes and Metabolism, 2010
The metabolic effect of insulin pump therapy depends on precise adjustments of insulin to food intake ratio. Calculation of prandial insulin dose is a complex process employing many variant factors such as pre-prandial glucose and carbohydrate (CHO ...
Marlena Błazik, Ewa Pańkowska
doaj  

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Insulin pump therapy:A practical guide to optimising glycaemic control

, 2014
Insulin pump services have been widely available in the UK for over 10 years. Despite this, the recent national Insulin Pump Audit identified that only 6% of patients with type 1 diabetes are managed with insulin pump therapy, far lower than anticipated.
Wilmot, Emma G., Grant, Paul, Choudhary, Pratik, Hammond, Peter   +3 more
core   +1 more source