Results 211 to 220 of about 3,853,066 (390)

Inhalable Hsa‐miR‐30a‐3p Liposomes Attenuate Pulmonary Fibrosis

Advanced Science, EarlyView.
The study explores inhalable hsa‐miR‐30a‐3p‐loaded liposomes as a treatment for bleomycin‐induced pulmonary fibrosis in mice. Hsa‐miR‐30a‐3p is electroporated into liposomes and formulated into a dry powder for inhalation. Delivered via dry powder inhalation, it improves pulmonary function, promotes myofibroblast de‐differentiation by targeting CNPY2 ...
Shuo Liu, Kristen D. Popowski, Christina M. Eckhardt, Weihang Zhang, Junlang Li, Yujia Jing, Dylan Silkstone, Elizabeth Belcher, Megan Cislo, Shiqi Hu, Halle Lutz, Asma Ghodsi, Mengrui Liu, Phuong‐Uyen C. Dinh, Ke Cheng   +14 more
wiley   +1 more source

The positive correlation between amphiregulin and insulin resistance. [PDF]

Endocr Connect
Zhao Y, Lu T, Wu M, Hu X, Xiang R, Feng M, Lu H.   +6 more
europepmc   +1 more source

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

Nature Reviews Neurology, 2018
S. Arnold, Z. Arvanitakis, Shannon L. Macauley-Rambach, A. Koenig, Hoau Yan Wang, R. Ahima, S. Craft, S. Gandy, C. Buettner, L. Stoeckel, D. Holtzman, D. Nathan   +11 more
semanticscholar   +1 more source

The Diminution of R‐Loops Generated by LncRNA DSP‐AS1 Inhibits DSP Gene Transcription to Impede the Re‐Epithelialization During Diabetic Wound Healing

Advanced Science, Volume 12, Issue 12, March 27, 2025.
Down‐regulated LncRNA DSP‐AS1, the diminution of R‐loop formation, reduced Ten‐eleven translocation 3 (TET3) occupancy, inhibited DNA demethylation at the DSP promoter, and disrupted re‐epithelialization process proceed sequentially during delayed diabetic wound healing.
Chen Yang, Hong Lian, Hengli Luo, Chenlin Song, Jianghong Lin, Zhuoxian Liang, Yulin Yang, Xiaosi Hong, Shaohua Li, Yanbo Chen, Liangyan Wu, Li Yan, Sifan Chen, Meng Ren   +13 more
wiley   +1 more source

Exploring the TyG Index and the Homeostasis Model Assessment of Insulin Resistance as Insulin Resistance Markers: Implications for Fibromyalgia Management and Understanding-A Narrative Review. [PDF]

Diagnostics (Basel)
Samavarchitehrani A, Mercantepe F, Behnoush AH, Klisic A.   +3 more
europepmc   +1 more source

Roles of insulin resistance and beta-cell dysfunction in dexamethasone-induced diabetes. [PDF]

, 1992
Ai Ogawa, John H. Johnson, Makoto Ohneda, Chris T. McAllister, Lindsey Inman, Tausif Alam, R H Unger   +6 more
openalex   +1 more source

Pharmacological Dissection Identifies Retatrutide Overcomes the Therapeutic Barrier of Obese TNBC Treatments through Suppressing the Interplay between Glycosylation and Ubiquitylation of YAP

Advanced Science, Volume 12, Issue 11, March 20, 2025.
This study reveals that obesity‐driven metabolic dysfunction enhances YAP O‐GlcNAcylation, facilitating its stabilization by preventing ubiquitylation and degradation via EIF3H, thereby driving TNBC progression and chemoresistance. Retatrutide disrupts this axis by suppressing O‐GlcNAcylation, restoring YAP ubiquitylation, and enhancing degradation ...
Xin Cui, Yueming Zhu, Lidan Zeng, Mengyuan Zhang, Amad Uddin, Theresa W. Gillespie, Lauren E. McCullough, Shaying Zhao, Mylin A. Torres, Yong Wan   +9 more
wiley   +1 more source

Predictive role of insulin resistance surrogates in gallstone disease. [PDF]

Medicine (Baltimore)
Liu J, Hu Z, Bo D, Zhang X, Zhang Z, Liu X.   +5 more
europepmc   +1 more source

Insulin Resistance in Humans

, 1982
Jerrold M. Olefsky
openalex   +1 more source

The insulin receptor: signalling mechanism and contribution to the pathogenesis of insulin resistance [PDF]

, 1991
H. U. H�ring
openalex   +1 more source