Results 211 to 220 of about 861,807 (357)

Insulin Resistance in Humans

, 1982
Jerrold M. Olefsky
openalex   +1 more source

Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles. [PDF]

, 1993
Gerald M. Reaven, Y D Chen, Jørgen Jeppesen, Pierre Maheux, Ronald M. Krauss   +4 more
openalex   +1 more source

Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen

Advanced Science, EarlyView.
This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang, Mingyue Fan, Su Chin Heo, Sheila M. Adams, Thomas Li, Yuchen Liu, Qing Li, Claudia Loebel, Jason A. Burdick, X. Lucas Lu, David E. Birk, Farid Alisafaei, Robert L. Mauck, Lin Han   +13 more
wiley   +1 more source

Severe Insulin Resistance Syndromes: Clinical Spectrum and Management. [PDF]

Int J Mol Sci
Pliszka M, Szablewski L.
europepmc   +1 more source

MCT1‐mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells

Advanced Science, EarlyView.
This study demonstrates that the transport of lactate to the mitochondria is of critical importance in determining the functions of macrophages by altering mitochondrial respiration. In macrophages, this lactate transport mechanism regulates glucose homeostasis by influencing the functions of insulin‐secreting cells in the pancreatic islets.
Lingling Chen, Yijun Lin, Xinyu Zhu, Shixuan Zhuo, Zixuan Li, Cheng Guo, Xiaoyi Ye, Jinzhu Chen, Shuying Wang, Yan Chen   +9 more
wiley   +1 more source

Publisher Correction: Chain splitting of insulin: an underlying mechanism of insulin resistance? [PDF]

NPJ Metab Health Dis
Cramer CN, Hubálek F, Brand CL, Helleberg H, Kurtzhals P, Sturis J.   +5 more
europepmc   +1 more source

Familial Type C Syndrome of Insulin Resistance and Short Stature with Possible Autosomal Dominant Transmission.

, 1989
Fumiko Nakamura, Masato Taira, Naotake Hashimoto, Hideichi Makino, Nozomu Sasaki   +4 more
openalex   +2 more sources

Insulin resistance is an important determinant of left ventricular mass in the obese. [PDF]

, 1993
Zion Sasson, Yosef Rasooly, T. Bhesania, Iris Rasooly   +3 more
openalex   +1 more source

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

Advanced Science, EarlyView.
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia, Xiaoyuan Jing, Ruoxi Wang, Mengke Su, Pei Wang, Yingxin Feng, Xiaohu Ren, Longfang Tu, Ping Wei, Zhen Lu, Yicong Jia, Feng Hong, Zhizhun Mo, Jiemeng Zou, Kang Huang, Caiyun Yan, Qianhui Zou, Liang Wang, Guoping Zhong, Zhi Zeng, Qiuliyang Yu, Wen Su, Xifei Yang, Fan Pan, Jianzhi Wang, Liping Wang, Lijun Kang, Paul J. Kenny, Zuxin Chen, Xin‐an Liu   +29 more
wiley   +1 more source

Roles of insulin resistance and beta-cell dysfunction in dexamethasone-induced diabetes. [PDF]

, 1992
Ai Ogawa, John H. Johnson, Makoto Ohneda, Chris T. McAllister, Lindsey Inman, Tausif Alam, R H Unger   +6 more
openalex   +1 more source