Results 311 to 320 of about 4,252,621 (405)

Frontiers in Nondrug Treatment of Sarcopenia: A Review of Pathological Mechanisms and the Latest Treatment Strategies

AGING MEDICINE, EarlyView.
This article mainly introduces the pathologic process of sarcopenia and the recent progress in diagnosis and treatment, especially the nondrug treatment. ABSTRACT Sarcopenia refers to the progressive decline and wasting of skeletal muscle function, typically linked to aging or as a secondary effect of various conditions, including systemic inflammation,
Qi‐Fei Kuang, Yu‐Qing Ni, You‐Shuo Liu   +2 more
wiley   +1 more source

Complex networks interactions between bioactive compounds and adipose tissue vis-à-vis insulin resistance. [PDF]

Front Endocrinol (Lausanne)
Barrera-Esparza M, Carreón-Torres E, Jiménez-Osorio AS, Angel-García J, Jiménez-Garza O, Flores-Chávez OR, Mendoza-Catalán GS, Estrada-Luna D.   +7 more
europepmc   +1 more source

Prognostic Value of Serum Insulin‐Like Growth Factor‐1 in Patients With Anal Fistula Treated by Incision‐Thread‐Drawing Surgery

Annals of Gastroenterological Surgery, EarlyView.
IGF‐1 levels above 174.9 ng/mL were associated with better wound healing and lower postoperative inflammation. Higher IGF‐1 levels correlated with improved anal function at 7 and 14 days post‐surgery. ABSTRACT Background Anal fistula is a chronic condition characterized by an abnormal tract between the anal canal and perianal skin, often leading to ...
Zhijun Wu, Xuexue Yin, Jing Li
wiley   +1 more source

Assessment of the Risk of Insulin Resistance in Workers Classified as Metabolically Healthy Obese. [PDF]

Nutrients
García Samuelsson M, Tárraga López PJ, López-González ÁA, Paublini H, Martínez-Almoyna Rifá E, Ramírez-Manent JI.   +5 more
europepmc   +1 more source

Selenium‐Containing Polyurethane Thermo‐Sensitive Hydrogel Accelerates Diabetic Wound Healing by Activating Unfolded Protein Response

Aggregate, EarlyView.
The selenium‐containing polyurethane (SePU) thermo‐sensitive hydrogel (SePU/HBC) was constructed by incorporating SePU into hydroxybutyl chitosan (HBC). This hydrogel alleviates endoplasmic reticulum stress (ERS) and inhibits cell apoptosis by activating the unfolded protein response (UPR), thereby promoting diabetic wound healing.
Mo Zhai, Zilun Huang, Banruo Xianyu, Xiaoqiang Bai, Zhuqing Wan, Yang Fu, Huaping Xu, Longwei Lv, Yongsheng Zhou   +8 more
wiley   +1 more source

Insulin Resistance in Type 1 Diabetes: Pathophysiological, Clinical, and Therapeutic Relevance.

Endocr Rev
Apostolopoulou M, Lambadiari V, Roden M, Dimitriadis GD.   +3 more
europepmc   +1 more source

Covalent binding of thioredoxin to TXNIP is required for diet-induced insulin resistance in the liver. [PDF]

J Biol Chem
Dagdeviren S, Hoang MF, Wang J, Goldberger T, Yu AM, Blair SJ, Benoit JC, Ricci-Blair EM, Melnik VY, Kim BY, Tauer LA, Scholz JJ, Worthmann A, Schlein C, Stone D, Deuitch NT, Aksentijevich I, Schnappauf O, Whited JL, Kim JK, Lee RT.   +20 more
europepmc   +1 more source

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

Aggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky, Olesya V. Stepanenko, Olga V. Stepanenko, Anna I. Sulatskaya   +3 more
wiley   +1 more source

Association among obesity, insulin resistance, and depressive symptoms: a mediation analysis. [PDF]

BMC Psychiatry
Xiao G, Lin C, Lan Q, Huang Z, Zhou C, Hu J, Cui Y, Wang L, Zhou B.   +8 more
europepmc   +1 more source