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Insulins for Insulin Resistance
Annals of Internal Medicine, 1981Excerpt To the editor: Dr. Galloway (1) notes in his comment on our article "U-500 Insulin in the Treatment of Antibody-Mediated Insulin Resistance" (2) that we did not compare equivalent doses of ...
David M. Nathan, Lloyd Axelrod
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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance.
Science, 1993Tumor necrosis factor-alpha (TNF-alpha) has been shown to have certain catabolic effects on fat cells and whole animals. An induction of TNF-alpha messenger RNA expression was observed in adipose tissue from four different rodent models of obesity and ...
G. Hotamisligil+2 more
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Insulin Resistance and Insulin Resistance Syndrome
2013METABOLISM AND HYPERTENSION Insulin Resistance Syndrome and Glycogen Synthesis, Roles of Muscle, Liver and Adipose Tissue, Hagit Eldar-Finkelman and Merav Yarkoni Hypertension and Insulin Resistance in the SJHR-Koletsky Rats, Jianhua Shao and Jacob Friedman Role of PTPase in Insulin Action and Insuln Resistance Recent Insights from Cellular and Animal ...
Eleazar Shafrir, Barbara C. Hansen
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Nursing Standard, 2003
Insulin resistance is one of the most important causes of premature death in developed countries (Turtle 2000). In this article, Alison Jeffery examines the basic pathology of insulin resistance and its effect on metabolic health. The role of the nurse is discussed in relation to prevention, health promotion and drug treatments for the management of ...
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Insulin resistance is one of the most important causes of premature death in developed countries (Turtle 2000). In this article, Alison Jeffery examines the basic pathology of insulin resistance and its effect on metabolic health. The role of the nurse is discussed in relation to prevention, health promotion and drug treatments for the management of ...
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Insulin Resistance and Insulin Sensitizers
Hormone Research in Paediatrics, 2001Insulin resistance is a key factor in the pathogenesis of type 2 diabetes mellitus and a co-factor in the development of dyslipidaemia, hypertension and atherosclerosis. The causes of insulin resistance include factors such as obesity and physical inactivity, and there may also be genetic factors.
Michael Stumvoll, Hans U. Häring
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Insulin resistance and hypertension
Molecular and Cellular Endocrinology, 1990Diminished insulin (Ins) sensitivity is a characteristic feature of various pathological conditions such as the cardiometabolic syndrome, Type 2 diabetes, and hypertension. Persons with essential hypertension are more prone than normotensive persons to develop diabetes, and this propensity may reflect decreased ability of Ins to promote relaxation and
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Hypertension and Insulin Resistance
Journal of Cardiovascular Pharmacology, 1992Insulin resistance and hyperinsulinemia is now recognized in non-insulin-dependent diabetes, essential hypertension, obesity, atherosclerotic heart disease, dyslipidemia, heart failure, and in heavy smokers. Several mechanisms have been proposed to explain hyperinsulinemia, insulin resistance and its relationship to hypertension; reduced sodium ...
D. J. Betteridge+3 more
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Immunologic insulin resistance
Diabetes, 1978The efficacy of sulfated beef insulin for plasma glucose control in 35 patients with immunologie insulin resistance was studied. Patients were on a mean dose of 550 U./day (range 200–2,000) of U-500 regular beef insulin. Mean maximum 125I-insulin-binding capacity was 191 mU./ml. serum (range 13–1,080).
John K Davidson, Donald W DeBra
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Alimentary Pharmacology & Therapeutics, 2005
SummaryBackground : Preliminary clinical and experimental results suggest that iron can modify hepatocytes’ insulin sensitivity by interfering with insulin receptor and intracellular insulin signalling.Aim : To evaluate in vivo the influence of iron on insulin resistance and insulin release in patients with non‐alcoholic fatty liver disease and in ...
A. Guzzo+7 more
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SummaryBackground : Preliminary clinical and experimental results suggest that iron can modify hepatocytes’ insulin sensitivity by interfering with insulin receptor and intracellular insulin signalling.Aim : To evaluate in vivo the influence of iron on insulin resistance and insulin release in patients with non‐alcoholic fatty liver disease and in ...
A. Guzzo+7 more
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