Results 131 to 140 of about 445,193 (314)

De-Intensification Of Blood Glucose Lowering Medication In People Identified As Being Over-Treated: A Mixed Methods Study

Patient Preference and Adherence, 2019
Huberta E Hart,1,2,* Kim Ditzel,1,* Guy E Rutten,1 Esther de Groot,1 Samuel Seidu,3 Kamlesh Khunti,3 Rimke C Vos1,4 1Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht University, Utrecht, The Netherlands; 2Leidsche ...
Hart HE, Ditzel K, Rutten GE, de Groot E, Seidu S, Khunti K, Vos RC   +6 more
doaj  

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

Advanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu, Edgar E. Perez Carbajal, Yih‐Chii Hwang, Sahil A. Mapkar, Benjamin W. Gilman, Sarah A. Bliss, Lam B. Tran, Kalgi T. Mehta, Jacob O. Banyasz, Ming Yu, Reynold R. Liu, Matthew N. Ly, Christapher S. Morrissey, Michael N. Wosczyna   +13 more
wiley   +1 more source

Inhalable Insulin: The Breakthrough in Insulin Therapy?

Annals of Saudi Medicine, 2001
I A, Harsch, E G, Hahn, J H, Ficker
openaire   +2 more sources

Adherence to insulin treatment in insulin-naïve type 2 diabetic patients initiated on different insulin regimens

, 2015
Dilek Gogas Yavuz, Sevim Ozcan, Oguzhan DeyneliDepartment of Endocrinology and Metabolism, Marmara University School of Medicine, Istanbul, TurkeyObjective: We aimed to evaluate adherence to insulin treatment in terms of treatment persistence and daily ...
Ozcan S, Deyneli O, Gogas Yavuz D
core  

Myocardial Insulin Resistance: An Overview of Its Causes, Effects, and Potential Therapy

, 2012
: Insulin resistance ensues when normal physiological concentrations of insulin are unable to induce effective cellular insulin signalling and glucose uptake by insulin sensitive tissues.
Daniel G., Eugene F. du Toit, Du Toit, Eugene, Donner, Dan   +3 more
core   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Exploring patients’ perceptions for insulin therapy in type 2 diabetes: a Brazilian and Canadian qualitative study

, 2010
Camila Guimarães2, Carlo A Marra1, Sabrina Gill1, Graydon Meneilly1, Scot Simpson3, Ana LPC Godoy2, Maria Cristina Foss de Freitas2, Regina HC Queiroz2, Larry Lynd11The University of British Columbia, Canada; 2University of São ...
et al, Camila Guimarães, Sabrina Gill, Carlo A Marra   +3 more
core  

Insulin and GLP-1 analogues in the treatment of type 1 Diabetes Mellitus.

, 2020
Insulin injections is the mainstay treatment in patients with type 1 diabetes. The dependence on insulin therapy in these patients is lifelong. Other drugs such as glucagon like peptide-1 (GLP-1) and its receptor agonists are considered to be effective ...
Sanni, Abdulsabur
core  

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Severe asparaginase-associated hypertriglyceridemia in pediatric acute lymphoblastic leukemia: a single-center experience

Frontiers in Oncology
BackgroundAsparaginase-associated hypertriglyceridemia (AAHTG) is a recognized metabolic complication of asparaginase therapy in pediatric acute lymphoblastic leukemia (ALL).
Maha Barbar, Maha Barbar, Dana Kanaan, Zebin AlZebin, Ammar Al Hmood, Sima Kalaldeh, Lana Amer, Saja Al Zghoul, Dana Aroury   +8 more
doaj   +1 more source