Precision Care for Hereditary Urologic Cancers: Genetic Testing, Counseling, Surveillance, and Therapeutic Implications. [PDF]
Somoto T +11 more
europepmc +1 more source
Subuniformity of harmonic mean p$$ p $$‐values
Abstract We obtain several inequalities on the generalized means of dependent p$$ p $$‐values. In particular, the weighted harmonic mean of p$$ p $$‐values is strictly subuniform under several dependence assumptions of p$$ p $$‐values, including independence, negative upper orthant dependence, the class of extremal mixture copulas, and some Clayton ...
Yuyu Chen +3 more
wiley +1 more source
Disclosure of onset-predictive biomarker results to research participants at risk of genetic frontotemporal dementia: a European perspective. [PDF]
Graafland CH +10 more
europepmc +1 more source
An observation‐driven state‐space model for claims size modelling
Abstract State‐space models are popular in econometrics. Recently, these models have gained some popularity in the actuarial literature. The best known state‐space models are of the Kalman‐filter type. These are called parameter‐driven because the observations do not impact the state‐space dynamics.
Jae Youn Ahn +2 more
wiley +1 more source
A propensity score-matched study including 250,000 patients with Factor V Leiden shows significantly increased mortality in comparison with individuals without thrombophilia. [PDF]
Hertel M +4 more
europepmc +1 more source
Optimal dividends for a NatCat insurer in the presence of a climate tipping point
Abstract We study optimal dividend strategies for an insurance company facing natural catastrophe claims, anticipating the arrival of a climate tipping point after which the claim intensity and/or the claim size distribution of the underlying risks deteriorates irreversibly.
Hansjörg Albrecher +2 more
wiley +1 more source
Dementia Prevention as the Neurovascular Dividend of Hypertension Control. [PDF]
Noriega de la Colina A, Leigh R.
europepmc +1 more source
Stagewise crop yield prediction with multisource functional indices
Abstract Index insurance design involves integrating weather data, soil moisture, phenology information, and satellite imagery, which presents challenges in data fusion. This article addresses the modelling of multisource functional indices of varying lengths by constructing a stagewise ensemble of sequential models.
Jing Zou, Ostap Okhrin
wiley +1 more source
What are the Chances of MACI Approval in the United States? A Deep Dive into the Insurance Authorization Data. [PDF]
Cavendish PA +6 more
europepmc +1 more source
Systemic Manifestations and Mortality Risk in Transthyretin V142I Variant Carriers: A Million Veteran Program Analysis. [PDF]
Sideris K +18 more
europepmc +1 more source

