Results 121 to 130 of about 1,780,198 (242)

L’ efficacité des instruments de gouvernance foncière de l’Union Africaine dans la prévention des conflits fonciers en Afrique : Quelles perspectives?

open access: yesPaix et Sécurité Internationales
L’Afrique est confrontée à une typologie diversifiée de conflits fonciers et, l’Union Africaine a adopté des directives foncières dans la perspective qu’elles contribuent significativement à la prévention des conflits fonciers. Cependant,
Ladislas Nze Bekale
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Informatique et intégration : le village planétaire est-il encore possible ?

open access: yes, 1999
International audienceDans son dernier livre, Delacôte écrit : « Et ne voilà-t-il pas le président Bill Clinton et le vice-président Al Gore venant à l'Exploratorium, en septembre 1995, annoncer au pays le câblage de toutes les écoles du pays d'ici l'an ...
Plantard, Pascal
core   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Mettre en pratique le tourisme durable : Le cas de l’auberge écotouristique Cree Village Ecolodge de Moose Factory, en Ontario

open access: yesTéoros, 2012
Afin de s’orienter vers la viabilité, le tourisme doit contribuer à l’autonomisation des collectivités locales. Ceci peut être réussi au moyen de la participation de la collectivité à la prise de décision où l’information essentielle est obtenue et aux ...
Sonya R. GRACI
doaj  

The immigrant/native wealth gap in Germany, Italy and Luxembourg [PDF]

open access: yes
This paper analyses the existence of an immigrant/native wealth gap by using household survey data for Luxembourg, Germany and Italy. The results show that, in all three countries, a sizeable wealth gap exists between natives and immigrants.
Sierminska, Eva   +2 more
core  

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