Results 141 to 150 of about 1,780,198 (242)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The Influence of Chinese Cultural Symbols on Attitudes Towards Ethnic Integration: The Moderating Role of Ethnic Identity. [PDF]
Int J PsycholSu S, Wan M, Yang B.
europepmc +1 more source
Actualisation d'une intégration non formulée
, 1990 Le Huu Khoa. Actualisation d'une intégration non formulée. In: Hommes et Migrations, n°1134, juillet 1990. Populations du Sud-Est Asiatique.
Lê, Hữu khóa
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Luxemburg's corporatist Scandinavian welfare system and incorporation of migrants [PDF]
Luxembourg is the EU and OECD member state (MS) with a permanently increasing immigra-tion and the highest share of immigrants and cross border commuters within the labour force and more so within the competitive sector.
HARTMANN HIRSCH Claudia, AMETEPE Kossi
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Les échanges économiques comme facteur d’intégration régionale dans le bassin du lac Tchad
Mu Kara SaniL’économie du bassin du lac Tchad est basée sur l’agriculture, l’élevage, le commerce, la pêche et l’artisanat. Cette zone entretenait d’étroites relations commerciales, basées sur l’exportation de bétail, l’importation des produits et divers articles en
Aboukar ABBA TCHELLOU
doaj
Sustainability of infectious disease elimination: a scoping review on integrating treatment and surveillance within health systems. [PDF]
BMJ OpenBaker MC +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source