Results 31 to 40 of about 1,576,833 (200)
La crise des accommodements raisonnables au Québec : quel impact sur l’identité collective ?
Cahiers du MIMMOC, 2016 Cet article se propose d’explorer l’impact du 11 septembre sur la notion du vivre ensemble au sein de la société canadienne, caractérisée, à l’instar de son voisin américain, par une diversité de cultures.
Ariane LE MOING
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Exploring the impact of violence in video games
eLifePlaying a violent game for a few weeks did not alter neural and behavioral responses to the pain of others in inexperienced male gamers.
Nicolas Roy, Michel-Pierre Coll
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Parcours de migrants et recomposition des sociétés d’accueil
Revue de Géographie Alpine, 2015 Nous avons mené en Bas-Valais durant les années 2011 et 2012 une étude de terrain pluridisciplinaire qui avait pour ambition de rendre compte des mécanismes de l’immigration et de l’intégration à un niveau très local et au plus près de l’expérience de ...
Thierry Amrein
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Unitas multiplex, ou pour un autre discours sur l’Europe [PDF]
Synergies Roumanie, 2018 Le discours actuel sur l’Europe est loin de servir la cause de l’intégration européenne. Conçu il y a 60 ans pour servir à des fins précises dans le contexte de l’époque, il est aujourd’hui mal adapté aux besoins identitaires des Européens.
Radu Albu-Comănescu
doaj
L'intégration « à la française » : une philosophie à l'épreuve des réalités
Revue Européenne des Migrations Internationales, 2006 Integration «the French way»: a doctrine confronted to hard facts. Some ten European Union countries have recently engaged in programmes to accommodate and integrate immigrants.
Jacqueline Costa-Lascoux
doaj +1 more source